Introduction: The amount of expression of BAX and BCL-2 genes in infertile men’s sperm as well as its association with sperm parameters and DNA fragmentation index is an issue which has not been studied yet. In this research, it is assumed that up-regulation of BAX and downregulation of BCL-2 are directly associated with sperm DNA fragmentation. Methods: After obtaining semen samples from the ...

background: use of cellular phones emitting radiofrequency electromagnetic field (rf-emf) has been increased exponentially and become a part of everyday life. this study aimed to investigate the effects of in vitro rf-emf exposure emitted from cellular phones on sperm motility index, sperm dna fragmentation and seminal clusterin (clu) gene expression. materials and methods: in this prospective ...

introduction: the amount of expression of bax and bcl-2 genes in infertile men’s sperm as well as its association with sperm parameters and dna fragmentation index is an issue which has not been studied yet. in this research, it is assumed that up-regulation of bax and downregulation of bcl-2 are directly associated with sperm dna fragmentation. methods: after obtaining semen samples from the p...

introduction: tegrity is the most important component for transferring genetic information sperm dna fragmentation is considered a component of male infertility. its assessment comprises conventional semen analysis of which emphasis is placed on its evaluation in fertility clinics. in this study, we investigate the relationship between sperm parameters of motility, morphology, concentration, an...

Background: One of the major factors affecting on male infertility is oxidative stress (OS). Two main sources of ROS production are leukocytes and spermatozoa. The ROS such as tertiary-butyl hydroperoxide (TBHP) may damage and fragmentate to sperm DNA, which can lead to complications in the offspring. In this study, we will investigate the effect of od on DNA fragmentation index (DFI) in sperm ...

background: although the effectiveness of ginger as an antioxidant agent has been exploited, little human research has been conducted on its activity on male reproductive functions. objective: this study was designed to investigate the effects of ginger (zingiber officinale) on sperm dna fragmentation (sdf) in infertile men. materials and methods: this randomized double-blind, placebo-controlle...

conclusions in our study, no prominent effect was seen; therefore, in order to have a better perspective of crocin activity against cancerous cell lines, further studies are highly recommended. results the highest concentration of crocin significantly decreased ros production after 48 hours of treatment. however, crocin had no effect on the expression level of hsp (heat shock protein). addition...

prolonged local consumption of anethum graveolens leaves, as an antihyperlipimic and antihypercholesterolemic agent, has been associated in some patients with skin disorders such as darkening and pigmentation mainly in the exposed areas such as face and hands.anethum graveolens belongs to the umbelliferae family which is belived to be rich in photoactive furocoumarins. an oraganic extract of th...

background: the initial step in the diagnostic investigation of male infertility has been traditionally based on the conventional seminal profile. however, there are significant limitations regarding its ability to determine the underlying mechanisms that cause the disorder. sperm dna fragmentation has emerged as a potential causative factor of reproductive failure and its assessment has been s...