نتایج جستجو برای: DMSA coated

تعداد نتایج: 48020  

2012
Qiuli Wu Yiping Li Meng Tang Dayong Wang

Dimercaptosuccinic acid (DMSA) coating improves the uptake efficiency presumably by engendering the Fe(2)O(3)-NPs. In the present study, we investigated the possible environmental safety concentrations of Fe(2)O(3)-NPs using different assay systems in nematode Caenorhabditis elegans with lethality, development, reproduction, locomotion behavior, pharyngeal pumping, defecation, intestinal autofl...

Journal: :nanomedicine journal 0
faranak mansouri falavarjan branch, islamic azad university, isfahan, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) gholamreza amiri falavarjan branch, islamic azad university, isfahan, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch) mahnoosh fatemi falavarjan branch, islamic azad university, isfahan, iranسازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (islamic azad university science and research branch)

objective(s): according to the unique properties of magnetic nanoparticles, their usages in medicine and industry have increased in the last decade. due to the vital role of liver in the body, the accumulation of cofe2o4 and cofe2o4@dmsa was studied. materials and methods:the nanoparticles were synthesized by co-precipitation method and were coated with dmsa. the techniques xrd, tem, dls, ftir,...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2013
Raquel Mejías Lucía Gutiérrez Gorka Salas Sonia Pérez-Yagüe Teresa M Zotes Francisco J Lázaro María P Morales Domingo F Barber

Although iron oxide magnetic nanoparticles (MNP) have been proposed for numerous biomedical applications, little is known about their biotransformation and long-term toxicity in the body. Dimercaptosuccinic acid (DMSA)-coated magnetic nanoparticles have been proven efficient for in vivo drug delivery, but these results must nonetheless be sustained by comprehensive studies of long-term distribu...

Journal: :iranian journal of biotechnology 2014
parisa hajshafii soheil fatahian kahin shahanipoor

background: recently, applications of nanoparticles in many fields of medicine have been developed, due to their specific physical and chemical properties. therefore assessment of their toxicity specially in the in vivo condition is necessary. objectives: the aim of this study is to evaluation the effect of fe3o4 nanoparticles coating by biocompatible compounds on their toxicity and also compar...

Journal: :Nanomedicine 2021

Aim: Superparamagnetic cubic iron oxide nanoparticles (IONPs) were synthesized and functionalized with meso-2,3-dimercaptosuccinic acid (DMSA) as a potential agent for cancer treatment. Methods: Monodisperse IONPs high value of saturation magnetization by thermal decomposition method DMSA via ligand exchange reaction, their cytotoxic effects on HeLa cells investigated. Results: an edge length 2...

2015
Zeinab Ghasemian Daryoush Shahbazi-Gahrouei Sohrab Manouchehri

BACKGROUND Magnetic Nanoparticles (MNP) have been used for contrast enhancement in Magnetic Resonance Imaging (MRI). In recent years, research on the use of ferrite nanoparticles in T2 contrast agents has shown a great potential application in MR imaging. In this work, Co0.5Zn0.5Fe2O4 and Co0.5Zn0.5Fe2O4-DMSA magnetic nanoparticles, CZF-MNPs and CZF-MNPs-DMSA, were investigated as MR imaging co...

Kahin Shahanipoor Parisa Hajshafii Soheil Fatahian

Background: Recently, applications of nanoparticles in many fields of medicine have been developed, due to their specific physical and chemical properties. Therefore assessment of their toxicity specially in the in vivo condition is necessary. Objectives: The aim of this study is to evaluation the effect of Fe3O4 nanoparticles coating by biocompatible compounds on their t...

Journal: Nanomedicine Journal 2016
Faranak Mansouri Gholamreza Amiri, Mahnoosh Fatemi

Objective(s): According to the unique properties of magnetic nanoparticles, their usages in medicine and industry have increased in the last decade. Due to the vital role of liver in the body, the accumulation of CoFe2O4 and CoFe2O4@DMSA was studied. Materials and Methods:The nanoparticles were synthesized by co-precipitation method and were coated with DMSA. The techniques XRD, TEM, DLS, FTIR,...

2013
Gaoyuan Ge Hengfang Wu Fei Xiong Yu Zhang Zhirui Guo Zhiping Bian Jindan Xu Chunrong Gu Ning Gu Xiangjian Chen Di Yang

One major obstacle for successful application of nanoparticles in medicine is its potential nanotoxicity on the environment and human health. In this study, we evaluated the cytotoxicity effect of dimercaptosuccinic acid-coated iron oxide (DMSA-Fe2O3) using cultured human aortic endothelial cells (HAECs). Our results showed that DMSA-Fe2O3 in the culture medium could be absorbed into HAECs, and...

Journal: :ACS applied nano materials 2022

This work aims at studying how the transformations that magnetic nanoparticles suffer in vivo affect their heating properties frame of hyperthermia treatments. Iron oxide (≈13 nm) with two different coatings [PMAO (polymaleic anhydride-alt-1-octadecene) and DMSA (dimercaptosuccinic acid)] have been subjected to an accelerated degradation a medium simulating lysosome conditions. The particles ph...

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