Poly(ethylene-g-maleic anhydride) (PEMA)/graphene nanoplatelets (xGn) (PEMA-xGn) composites were prepared by melt dispersion in an internal shear mixer. By adding dicumyl peroxide (DCP), cured poly(ethylene-g-maleic anhydride) C-PEMA was also produced. Different amounts of xGn were introduced into the PEMA in range of 0.5–5 wt. %. The effects of the sequence of feeding additives into the mixer ...

AIM Des-γ-carboxyprothrombin (DCP) has been used as a tumor marker for hepatocellular carcinoma (HCC). Recently the DCP/NX-DCP ratio, calculated by dividing DCP by NX-DCP, has been reported useful in detecting HCC. The purpose of this study is to clarify the significance of DCP and NX-DCP expression in HCC tissues. METHODS HCC and non-HCC tissue samples were obtained from 157 patients and wer...

Abstract We prepared different thermoplastic elastomers (TPEs) using an internal mixer. investigated the properties of polyurethanes (TPUs) produced from prepolymers with various isocyanate content and two chain extenders to select most appropriate TPU matrix for preparing vulcanizates (TPVs). Based on results, we selected a prepolymer moderate (10%) more flexible 1,6-hexanediol as extender TPV...

Patients with hepatocellular carcinoma (HCC) who respond to sorafenib have been reported to exhibit an increase in the level of des-γ-carboxyprothrombin (DCP) in the blood, subsequent to the initiation of sorafenib treatment. In the present study, the levels of secretion of DCP and DCP with more γ-carboxyglutamic residues (NX-DCP) and the effects of hypoxic conditions were examined in 13 liver ...

Serum des-gamma-carboxy prothrombin (DCP) is commonly used to detect hepatocellular carcinoma (HCC). This review focuses on the clinical features of DCP-positive HCC and the molecular function of DCP in HCC. DCP-positive HCC demonstrates more aggressive clinicopathological features than DCP-negative HCC. Analysis of the biological effects of DCP revealed that DCP acts as a growth factor in both...

Des-γ-carboxy prothrombin (DCP) is a prothrombin precursor produced in hepatocellular carcinoma (HCC). Because of deficiency of vitamin K or γ-glutamyl carboxylase in HCC cells, the 10 glutamic acid (Glu) residues in prothrombin precursor did not completely carboxylate to γ-carboxylated glutamic acid (Gla) residues, leaving some Glu residues remained in N-terminal domain. These prothrombin prec...

Controversies about the combination of des-gamma-carboxyprothrombin (DCP) and alpha-fetoprotein (AFP) for hepatocellular carcinoma diagnosing still exist. Hence, we performed this updated meta-analysis to estimate the diagnostic value of DCP , AFP and DCP + AFP in HCC. In addition, we conducted a validation study to analyze the performance of the candidate makers. After a systematic literature ...