the objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...

Abstract This study aimed to obtain the optimum formula of Chlorella milk with D-Optimal Mixture Design and determine consumer preference for formula. research method was divided into formulation response design, hedonic test, analysis, optimization, verification The determined based on highest score taste. Two solutions were obtained, it found that 0.40% + 0.05% vanillin 4.55% sugar most prefe...

The equivalence theorem is the most important of experimental design. For single response, D-optimal continuous design and equal allocation already exist. However, for multiresponse mixture experiments has not been investigated. In this paper, we study problem find that maximize variance function to number response. designs are illustrated by two examples.

Functional foods are in great demand worldwide because of their many health benefits. As milk is a nutrient-dense diet that comprises all vital nutrients, it can be utilized as the primary base to produce variety functional foods. Ginger, cinnamon and pumpkin possess tremendous nutritional therapeutic properties such stimulating digestive system, lowering blood cholesterol levels exhibiting ant...