Studies for this thesis involve efforts toward the enantioselective total synthesis of taxusin (5). Key features of the synthetic sequence include a diastereoselective, intramolecular enone-olefin [2+2] photocyclization of photosubstrate 94 which introduces the correct stereochemistry of the C(8) methyl group. This reaction represents an unprecedented total reversal of stereochemistry from the ...

body's iterative force-field computer program has been used to calculate strain energies in cyclooctanone (i). 348 mhz 1h nmr spectra of (i) have been investigated over the temperature range of 25° to -160°c. two conformation processes affect the 1h nmr spectrum of (i). iterative force-field calculations on the conformations and conformational interconversion paths of (i) give results consisten...

Body's iterative force-field computer program has been used to calculate strain energies in cyclooctanone (I). 348 MHZ 1H NMR spectra of (I) have been investigated over the temperature range of 25° to -160°C. Two conformation processes affect the 1H NMR spectrum of (I). Iterative force-field calculations on the conformations and conformational interconversion paths of ...