systemic sclerosis is a generalized disorder of connective tissue, in which the pattern of disease extent, progression and outcome is heterogenous. to determine clinical features, disease extent and progression, we studied our patients in two phases of disease early (the first 3 years) and late phases (after 6 years of disease). 19 patients had diffuse cutaneous and 34 patients had limited cuta...

abstract background glucantime is the first line agent for treatment of cutaneous leishmaniasis (cl). it has adverse effects on blood elements. this research has been done to evaluate the blood complications of this medicine in patients with cutaneous leishmaniasis. methods this clinical trial was done at nikpour clinic, yazd, iran. blood samples were collected from patients diagnosed with cl b...

background: cutaneous leishmaniasis is an endemic disease in many regions of iran, including the city of mashhad. in recent years, some cases have not responded to glucantime, the usual treatment for this disease. the cellular immune response caused by t-helper type 1 (th1) cells has an important role in protection against leishmaniasis, and activation of the t-helper type 2 (th2) response caus...

sarcoidosis is multi organ disease with cutaneous manifestation in 20%-35% patients. cutaneous sarcoidosis has variable manifestations that make it difficult to diagnose. so clinical, histopathologic and laboratory evaluation is needed for diagnosis. most of cutaneous lesions presents as nodul, maculopapule and plaque. morpheaform lesion is a rare presentation of cutaneous sarcoidosis. this cas...

occurrence of cutaneous metastasis of gastrointestinal cancer is uncommon, with a reported frequency of less than 5 percent.they can occur as the first sign of disease recurrence in a treated patient or as a sign of terminal disseminated cancer or rarely as the first manifestation of an occult malignancy. the cases reported here represent three different manifestation of cutaneous metastasis of...

the aim of this study was to measure the alterations in serum zinc (zn) copper (cu) and iron (fe) concentrations in patients with acute and chronic cutaneous leishmaniasis. serum zinc and copper were measured by flameless atomic absorption spectrophotometer and serum iron concentration was measured by the ferrozine method with commercial kits and assay was carried out by using an automatic anal...

cutaneous leishmaniasis may present with clinical presentation such as zosteriform, sporotrichoid and erysipeloid. the eczema variant has rarely been reported. we report a 27- year- old patient with atypical cutaneous leishmaniasis resembling eczema on the hand of a man in yazd province in the central of iran.

due to the high prevalence of anthroponotic cutaneous leishmaniosis (acl) in barn city, a survey was carried out to determine epidemiological characteristics of acl in barn in 1992. for this purpose, 23 out of the total 51 schools (elementary, junior high and senior high) were randomly selected and 6053 students were examined. the prevalence of acute sores and scars were 2% and 17% respectively...

conclusions according to the epidemiological features of cl in iran, providing a uniform mechanism for control and prevention of this disease is not possible. thus, initial actions such as staff training, screening in endemic areas, and treatment of patients with urban leishmaniasis as a reservoir for the disease can be useful, according to the geographical position and carrier. results most of...

chrysomya bezziana villeneuve is the most important fly, which produces myiasis, exists as an obligate ectoparasite in the ani­mals, and afflicts human. poor hygiene and working in contaminated areas particularly during warm seasons provide a situa­tion to infest by this parasite. infestation in human and livestock are often observed in wounds, normal body orifices such as eyes, ears, nose, and...