Cocculus hirsutus Linn was studied for antimicrobial activity against Staphylococcus aureus, Echerchia coli, Pseudomonas aeruginosa and Salmonella typhi using agar disc-diffusion method. Petroleum ether extract, Ethanolic extract and Crude alkaloidal fraction were screened for the activity in various concentrations and zone of inhibitions were recorded. Results suggest that the Ethanolic extrac...

In the present work, the antinociceptive action was assayed in several experimental models in mice: writhing, formalin and hot plate tests. The crude alkaloid fraction (25, 50, 100 mg/ ???????? ???????? ?????? ???? ?????????????????????????????? ?????????????? ?????????????????????????? ???????????????? ???????? ???????????????????????? ?????? ?????????????? ?????????? intraperitoneal inject...

In the present work, the antinociceptive action was assayed in several experimental models in mice: writhing, formalin and hot plate tests. The crude alkaloid fraction (25, 50, 100 mg/ ???????? ???????? ?????? ???? ?????????????????????????????? ?????????????? ?????????????????????????? ???????????????? ???????? ???????????????????????? ?????? ?????????????? ?????????? intraperitoneal inject...

In the present study the methanolic extract of Albizia gummifera was fractionated into various fractions. These fractions were tested against choroquine sensitive (NF54) and resistant (ENT30) strains of Plasmodium falciparum. All other fractions apart from the alkaloidal fraction showed low activity with IC 50 above 3 microg/ml. The alkaloidal fraction exhibited strong activity against NF54 and...

the isolation and characterization of two new isoquinoline alkaloids, dehydropuntarenine and dehydrosaulatine, obtained during the column chromatography of an alkaloidal fraction from the roots of b. actinacantha (berberidaceae) are described.

In the present work the pharmacological activities of SFE extracts from T. catharinensis were evaluated. The SFE extracts were obtained using supercritical CO2 plus ethanol as cosolvent (4.6 and 9.2% m/m) at pressures of 250 and 300 bar and temperatures of 35, 45, and 55oC. The crude extracts were solvent-fractionated (hexanic fraction, alkaloid, and aqueous fractions) and analyzed by Thin-laye...

The isolation and characterization of two new isoquinoline alkaloids, Dehydropuntarenine and Dehydrosaulatine, obtained during the column chromatography of an alkaloidal fraction from the roots of B. Actinacantha (Berberidaceae) are described.

Erythrina abyssinica Lam. is an important medicinal plant growing in Sudan; its seeds were investigated for the first time for their alkaloidal constituents and biological activity. The in vitro cytotoxicity of the crude alkaloidal fraction (CAF) against the cell lines HeLa, Hep-G2, HEP-2, HCT116, MCF-7 and HFB4 showed promising activity, with IC₅₀ values of 13.8, 10.1, 8.16, 13.9, 11.4 and 12....

One adenoma and one adenocarcinoma of the islet cells and one adenoma of the exocrine pancreas were found in 3 out of 15 rats given a single dose (500 to 1500 mg/kg body weight) of pyrrolizidine alkaloids from Amsinckia intermedia Fisch and Mey (Boraginaceae), tarweed, a plant known to cause livestock losses from liver damage in the United States. Among rats treated with Heliotropium supinum L....