OBJECTIVE Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever. In this study, we measured serum adenosine deaminase and xanthine oxidase levels in Crimean-Congo hemorrhagic fever patients. METHODS Serum adenosine de...

BACKGROUND & OBJECTIVES Crimean - Congo hemorrhagic fever is an acute viral hemorrhagic fever with considerable mortality. Despite increasing knowledge about hemorrhagic fever viruses, the pathogenesis of Crimean -Congo hemorrhagic fever and causes of death were not well described. We aimed to evaluate whether there were electrocardiographic parameters designating mortality among these patients...

368 www.thelancet.com/infection Vol 17 April 2017 1 Haider S, Hassali AM, Iqbal Q, et al. Crimean-Congo haemorrhagic fever in Pakistan. Lancet Infect Dis 2016; 16: 1333. 2 Müller MA, Devignot S, Lattwein E, et al. Evidence for widespread infection of African bats with Crimean-Congo hemorrhagic fever-like viruses. Sci Rep 2016; 6: 26637. 3 Mourya DT, Yadav PD, Shete AM, et al. Cross-sectional se...

BACKGROUND Crimean-Congo hemorrhagic fever was rarely reported from Iran before 1999. In a recent outbreak, the disease has been reported from different provinces of Iran, especially from Sistan and Baluchestan. Ribavirin has been recommended by World Health Organization as a potential therapeutic modality for Crimean-Congo hemorrhagic fever. This study was conducted to determine the clinical o...

To confirm the presence of Crimean-Congo hemorrhagic fever in Sudan, we tested serum of 8 patients with hemorrhagic fever in a rural hospital in 2008. Reverse transcription-PCR identified Crimean-Congo hemorrhagic fever virus. Its identification as group III lineage indicated links to virus strains from South Africa, Mauritania, and Nigeria.

1. Grard G, Drexler JF, Fair J, Muyembe JJ, Wolfe ND, Drosten C, et al. Re-emergence of Crimean-Congo hemorrhagic fever virus in Central Africa. PLoS Negl Trop Dis. 2011;5:e1350. http://dx.doi. org/10.1371/journal.pntd.0001350 2. Mild M, Simon M, Albert J, Mirazimi A. Towards an understanding of the migration of Crimean-Congo hemorrhagic fever virus. J Gen Virol. 2010;91:199–207. http://dx.doi....

Crimean-Congo hemorrhagic fever is a tick-borne viral disease reported from more than 30 countries in Africa, Asia, South-East Europe, and the Middle East. The majority of human cases are workers in livestock industry, agriculture, slaughterhouses, and veterinary practice. Nosocomial transmission is also well described. Clinical manifestations are nonspecific and symptoms typically include high...

background and aims: crimean-congo hemorrhagic fever (cchf) is a fatal viral disease that occurs in approximately 30 countries. it has the most extensive geographic range among the tick-borne viruses that affect human health. cchf viruses have a tripartite rna genome consisting of large (l), medium (m) and small (s) segments. this study was undertaken to determine the genetic relationship of cc...

background crimean-congo hemorrhagic fever (cchf) is a tick-borne disease caused by arbovirus which can be transmitted to human by several routes. tick bite and living in a rural area have been the most common factors for inception of cchf in adults and children in studies reported from iran. objectives this study was conducted to detect the disease acquisition routes among children with confir...