the aim of this study was to investigate the effect of acute swimming stress on plasma corticosterone and leptin levels in female and male rats. thirty- seven adult male (n=20) and female (n=20) sprague dawley rats (200-250 g weight) were used. the leptin and corticosterone levels were measured following swimming stress (10 minutes) or no stress. plasma leptin and corticosterone were measured b...

The overactive hypothalamic–pituitary–adrenal (HPA) axis is believed to trigger the overproduction of corticosterone, leading neurotoxicity in brain. Fisetin a flavonoid commonly found fruits and vegetables. It has been suggested possess various biological activities, including antioxidant, anti-inflammatory, neuroprotective effects. This study aims explore potential properties fisetin against ...

Background: Depression is a common mood disorder that in the long-term impairs thoughts, behavior, feelings, and health. Chronic unpredictable stress is one of the factors that can cause depression. Objectives: To investigate the effect of voluntary exercise training on immobility behavior (caused by chronic unpredictable stress) and serum corticosterone concentration. Materials & Methods: A ...

Introduction: The lack of social communication is associated with the primary risk of proper brain functions. It is reported that crocin helps relieve this problem. The present study examined the protective effect of two doses of crocin on Long-term potentiation (LTP) of hippocampal cornu ammonis 1 (CA1) area as a cellular mechanism in rats exposed to chronic social isolated stress. Methods: R...

Background and Objective: It is well known that stress and glucocorticoid, modulate memory processing, though the result is completely dependent on the time of stress induction. This study investigated the effect of acute corticosterone administration on memory retrieval of recent and remote memory in a 4 trials/day (low- intensity learning) or 8 trials/ day (high- intensity learning) Morris wa...

Introduction: Depression is one of the most frequent psychiatric disorders in the world with occurs with higher incidence in women. In the present study, the effect of water-alcoholic extract of Papaver rhoeas L. on forced swimming test (FST) in Swiss-Webster mice were examined. Methods: We used Swiss-Webster mice (20-25 g) to execute FST on them. The plant extract (1, 10, 30, a...

introduction: the concentration of noradrenalin and corticosterone as the two nociception modulators change after fasting or stress situation. the aim of present study was to investigate the effect of food deprivation on formalin-induced nociceptive behaviours and plasma levels of noradrenalin and corticosterone in rats. methods: food was withdrawn 12, 24 and 48 h prior to performing the formal...

the aim of this study was to analyze the stress response during 3 hours net confinement stress and recovery period of 22 hours in normal (std) and in 17α-hydroxylase deficient common carp (e5). fish were raised for 6 months and sampled at t0 (control, unstressed), 5 minutes, 20 minutes, 1 hour and 3 hours of exposure to net confinement, and after 1 hour, 4 hours, and 22 hours of recovery. at ev...