Genome-Wide Association Studies (GWAS) have identified genetic variants contributing to the risk of cardiovascular disease (CVD) at the chromosome 9p21 locus. The chromosome 9p21 is an important susceptibility locus for several multifactorial diseases like ischemic stroke, aortic aneurysm, type 2 diabetes mellitus and coronary artery disease (CAD). F7 gene because of its role in activating the ...

coronary artery calcium scoring (cacs) is a reasonable test for patients with the possibility of atherosclerosis. it can also be used for reclassifying the coronary artery disease (cad) to the high-risk status by higher cacs and subsequently modifying the management of the patients.the purpose of this study was to investigate the association of cacs to the severity of coronary artery disease in...

one of the leading causes of death in the world are cardiovascular diseases, among which coronary artery disease (cad) is the most common one. it occurs as a result of narrowing of the arteries which supply blood to the heart due to a theroma plaque formation. this kind of heart disease can be considered as a multifactorial one as genetic and environmental factors are involved in its incidence....

genome-wide association studies (gwas) have identified genetic variants contributing to the risk of cardiovascular disease (cvd) at the chromosome 9p21 locus. the chromosome 9p21 is an important susceptibility locus for several multifactorial diseases like ischemic stroke, aortic aneurysm, type 2 diabetes mellitus and coronary artery disease (cad). f7 gene because of its role in activating the ...

conclusions our findings revealed that the severity of coronary artery stenosis is common in diabetic patients compared to nondiabetics. early diagnosis and treatment of cad in diabetic patients is recommended. results based on data found in our study, 93.8% of diabetic and 83.4% of nondiabetic patients were shown to suffer coronary artery stenosis. severe involvement (grade 3vd) of coronary ar...

coronary artery disease is one of the most common causes of mortality and morbidity across the world. its treatment includes medical treatment, coronary artery bypass graft (cabg) and percutaneous coronary intervention (pci). the purpose of this study was to investigate the effect of pci on echocardiographic findings of left ventricular (lv) systolic and diastolic function. 115 patients with co...

abstract introduction: non-invasive measurement of carotid intima media thickness (imt) has been noted as a marker for atherosclerosis and can serve as a predictor of cardiovascular accidents. the present study investigates the relationship between carotid imt and coronary artery disease (cad). method: this is a descriptive, analytical cross-sectional study of 300 individuals referring to isfah...