objective midazolam is a significant and effective drug for control of a life-threatening condition, generalized and partial refractory convulsive status epilepticus. the goal of this study was evaluation of midazolam efficacy for management of this serious disease and its two side effects, hypotension and respiratory failure. materials & methods our study was done using a quasi experimental me...

Introduction: Status epilepticus (SE) is a neurological emergency in which prolonged seizures require rapid diagnosis and treatment. It classified as convulsive, non-convulsive, electrographic patterns. Neuroimaging findings associated with status may raise suspicion of ischemia, encephalitis, or neoplastic lesions possibly leading to additional studies surgical Further follow-up imaging preven...

introduction: epilepsy is a neural disorder in which abnormal plastic changes during short and long term periods lead to increased excitability of brain tissue. kindling is an animal model of epileptogenesis which results in changes of synaptic plasticity due to repetitive electrical or chemical sub-convulsive stimulations of the brain. lateral hypothalamus, as the main niche of orexin neurons ...

The risk of long-term mortality and its predictors following convulsive status epilepticus in childhood are uncertain. We report mortality within 8 years after an episode of convulsive status epilepticus, and investigate its predictors from a paediatric, prospective, population-based study from north London, UK. In the current study, we followed-up a cohort previously ascertained during a surve...

OBJECTIVE To investigate the characteristics of sustained muscle activation during convulsive epileptic and psychogenic nonepileptic seizures (PNES), as compared to voluntary muscle activation. The main goal was to find surface electromyography (EMG) features that can distinguish between convulsive epileptic seizures and convulsive PNES. METHODS In this case-control study, surface EMG was rec...

Forty-six female patients with pseudoseizures were compared with 50 female patients referred to a psychiatric outpatient clinic. Patients with convulsive pseudoseizures were more likely to be single and childless. An abnormal EEG was more frequently reported in patients with convulsive pseudoseizures, contributing to their earlier diagnosis of epilepsy. The defence mechanisms of patients with c...

non-convulsive status epilepticus (ncse) may present with several manifestations, many of which may not be obvious. the most important tool for the diagnosis of ncse is the electroencephalograph (eeg) pattern. this is a case report of a boy 9 years of age presenting with severe and continuous headache. he had received chemotherapy for histiocytosis, diagnosed at the age of 3.5 years. no evidenc...

Objective The prevalence of the non-convulsive type of late seizure after stroke is unknown. The aim of the present study was to clarify the characteristics of late seizure in clinical practice, mainly focusing on the prevalence of non-convulsive seizure. Methods A total of 178 consecutive patients who were admitted and diagnosed with late seizure after stroke were retrospectively enrolled, and...

INTRODUCTION Not all convulsive episodes are due to epilepsy and a number of these have a cardiovascular cause. Failure to identify these patients delays the provision of adequate therapy while at the same time exposes the individual to the risk of injury or death. METHODS We report on three patients who suffered from recurrent convulsive episodes, thought to be epileptic in origin, who were ...