comply with regulatory oversight and to be confident in the overall quality of the final product. Though there is some ambiguity in the industry as to the exact definition of validation, it is clear that all components of the sealing process that influence package integrity must be monitored, measured, and controlled. Moreover, equipment must perform the heat sealing function in a repeatable, i...

BACKGROUND Concern about inadvertently sealing over caries often prevents dentists from providing dental sealants. The objective of the authors' review was to examine the effects of sealants on bacteria levels within caries lesions under dental sealants. METHODS The authors searched electronic databases for comparative studies examining bacteria levels in sealed permanent teeth. To measure th...

AIM To evaluate the efficacy and safety of applying the LigaSure system (approved for vessel sealing) to intestine sealing procedures. METHODS Fifteen New Zealand rabbits underwent laparotomic intestinal resection of the cecum (7 animals, group 1) or small intestine (8 animals, group 2), sealing the stumps by applying precisely controlled electrothermal energy and physical pressure in an expe...

The sealing performance of end fittings is very important for offshore oil and gas pipelines. To investigate the sealing behavior of a ring-shaped wedge seal, global and local numerical models of the ring–pipe interaction have been developed based on the finite-element method. First, the sealing process of the ring under pressure is simulated. Second, a criterion for the penetration of fluid pr...

HYPOTHESIS An experimental polymeric sealant (CoSeal [Cohesion Technologies, Palo Alto, Calif]) provides equivalent anastomotic sealing to Gelfoam (Upjohn, Kalamazoo, Mich)/thrombin during surgical placement of prosthetic vascular grafts. DESIGN Randomized controlled trial. SETTING Nine university-affiliated medical centers. PATIENTS One hundred forty-eight patients scheduled for implanta...

PURPOSE The merits of laparoscopic sealing devices have been poorly characterized. The purpose of this study was to compare two bipolar sealing devices [LigaSure V (LS) and Gyrus PK (GP)], an ultrasonic device [Harmonic Scalpel ACE (HS)] and a novel device using nanotechnology [EnSeal PTC (ES)]. MATERIALS AND METHODS The ability of all four 5 mm devices to seal 5 mm bovine arteries was tested...

Zero-level packaging technology ensures dicing and handling compatibility of the MEMS device along with low cost by encapsulating the MEMS components using wafer level processing. It is also essential for providing the MEMS with a controlled ambient in a cost-effective way. In order to be compatible with a broad range of MEMS processes, IMEC developed sealing methods with a low temperature budg...

A large amount of heroin street doses are seized and examined for drug content by the Israel police. These are generally wrapped in heat-sealed plastic. Occasionally it is possible to visualize latent fingerprints on the plastic wrap itself, but the small size of the plastic item and the sealing process makes the success rate very low. In this study, the possibility of extracting and profiling ...

Design: A systematic search for randomized controlled trials comparing total tonsillectomies performed using vessel sealing systems (VSS), Harmonic Scalpel (HS), or radiofrequency ablation (ie, Coblation) with the conventional technique of cold steel and/or electrocautery dissection (CS/EC). Estimation of odds ratios and 95% confidence intervals (CIs), weighted mean differences (WMD), or standa...