objective(s) in the present study, the effects of aqueous-ethanolic extract from rosa damascena on heart rate and contractility were examined. materials and methods isolated guinea-pig hearts were perfused through aorta in a langendorff mode. heart rate (hr) and contractility were determined in the presence of four concentrations of the extract (0.1, 0.2, 0.4 and 1.0 mg %) and isoprenaline (1, ...

background : envenomation by hemiscorpius lepturus is not painful and the clinical manifestations include bloody urine due to hemoglobinuria or hematuria, dermonecrotic reactions,cardiac arrhythmia and in minority of cases acute renal failure which may lead to death following disseminated intravascular coagulation in infants. cardiac effects of envenomation by h. lepturus venom including inotro...

Objective(s) In the present study, the effects of aqueous-ethanolic extract from Rosa damascena on heart rate and contractility were examined. Materials and Methods Isolated guinea-pig hearts were perfused through aorta in a Langendorff mode. Heart rate (HR) and contractility were determined in the presence of four concentrations of the extract (0.1, 0.2, 0.4 and 1.0 mg %) and isoprenaline (...

It is a well-established fact that adenosine and its receptor subtypes (A 1 and A ) are involved in changes of contractility, heart rate and coronary blood flow (CBF) under different circumstances. This study was conducted to evaluate the role of nitric oxide and prostaglandins in development of these changes. For this purpose, Nitro-L-Arginine methyl ester (L-NAME), and indomethacin as inhibit...

background: there are controversial reports about the exact mechanisms of lead-induced hypertension, but many factors such as alteration in the responsiveness of cardiovascular system to endogenous substances including catecholamines could be one of the mechanisms involved. in present study, the effect of exposure to 100 ppm lead acetate by drinking water (in the periods of 4, 8 and 12 weeks) o...

Objective(s): An increase in nitric oxide (NO) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. Since minocycline has been shown to inhibit NO overproduction, we aimed to examine its role in a rat model of CCl4-induced cirrhotic cardiovascular complications. Materials and Methods: Portal pressure and inotropic responsiveness of isolated papillary muscles to is...

Background and Objective: Epidural analgesia (EA) has been used to relieve labor pain in many obstetric units, yet controversy persists about its effect on progress and outcome in labor. The purpose of the current study was to evaluate the effect of EA on the rate of cervical dilation and myometrial contractility. Methods: In a 6-month period, 36 women who received standardized EA were mat...

objective(s): an increase in nitric oxide (no) production has been reported in cirrhotic cardiomyopathy and, portal hypertension. since minocycline has been shown to inhibit no overproduction, we aimed to examine its role in a rat model of ccl4-induced cirrhotic cardiovascular complications. materials and methods: portal pressure and inotropic responsiveness of isolated papillary muscles to iso...

it is a well-established fact that adenosine and its receptor subtypes (a 1 and a ) are involved in changes of contractility, heart rate and coronary blood flow (cbf) under different circumstances. this study was conducted to evaluate the role of nitric oxide and prostaglandins in development of these changes. for this purpose, nitro-l-arginine methyl ester (l-name), and indomethacin as inhibit...

background: the marginal length from main tumor in esophageal cancer is a considerable issue regarding surgical management and adjuvant treatment; so we decided to study the contractility effect on the proximal surgical margin after immersing it in10% buffered formalin as a fixative. methods: the proximal marginal length of  ten sequential patients with esophageal cancer who underwent transhiat...