Objective(s): MicroRNAs (miRNAs) could regulate many cellular processes such as proliferation and differentiation. let-7a miRNA is one of the key regulators in the developmental transition of retinal progenitor cells into differentiated cells. Current evidence suggests that mesenchymal stem cells (MSCs) can isolate from various tissues such as bone marrow and conjuncti...

PURPOSE We wanted to investigate filaggrin expression in normal conjunctiva and in conjunctiva exposed to different degrees of mechanical stress. Mechanical stress results in parakeratinization of the conjunctiva. If filaggrin is expressed in the milder forms of parakeratinization, it might be used as a sensitive marker of mechanical stress. METHODS Immunohistochemical staining using antibodi...

Introduction To evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium. Methods: Total RNA was isolated from the human conjunctiva and central cornea. Those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea wer...

through the lower lid as a distinct swelling which becomes decidedly more prominent when the patient looks upwards. On everting the right lower lid, there is an ovoid cyst-like swelling occupying the middle third of the lower part of the ocular conjunctiva. The growth nearly approaches the fornix. It is somewhat adherent to the over-lying conjunctiva, and moves fairly freely over the sclerotic....

PURPOSE To investigate the role of Tafazzin (TAZ) protein in regulating the proliferation of normal human conjunctiva epithelial cells and epithelial cells from pterygium tissue. METHODS Conjunctiva epithelial cells were cultured in keratinocytes growth medium and treated with transformation growth factor β (TGFβ) to analyze the expression and translocation of TAZ protein by immunostaining an...

introduction to evaluate the expression patterns of cytokeratin (k) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether k13 could be used as a marker for conjunctival epithelium. methods: total rna was isolated from the human conjunctiva and central cornea. those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea were ...

purpose : to describe a case of bilateral squamous cell carcinoma in right nasal and left temporal conjunctiva, simulating bilateral pterygium case report : a reddish fibrovascular pterygium-like lesion was observed in the nasal side of bulbar conjunctiva on the right eye and temporal conjunctiva of the left eye. medical examination not revealed any coexistent malignancy elsewhere excisional bi...