Background: Goiter is not frequently seen in the neonatal period.Case report: We report the case of a full-term neonate who was born with anterior neck swelling and observed tosuffer from congenital goiter on examination. Thyroid function tests were within normal limits. Thyroid swellinggradually reduced in size during the 1st week of life. All the cases of congenital goiter t...

Background: Pseudo-Pendred syndrome (PPS) is a genetic disorder inherited as an autosomal recessive disorder. PPS characterized by the presence of hypothyroid goiter combined with mild to moderate form SNHL, not presentable at birth, no obvious inner ear malformation. This major difference from Pendred in which SNHL congenital, severe profound nature, and associated malformation, mostly enlarge...

A normal thyroid gland is difficult to distinguish from the surrounding tissues. Its enlargement, referred as goiter, most often found in newborn kids, less adult animals. Feeding errors, such incorrect iodine content ration or presence of goitrogens, may contribute its formation. The occurrence goiter also have a genetic basis. Mutation within TG gene leads abnormal synthesis thyroglobulin – p...

We describe two cases of fetal goiter in women with no history of thyroid disease. Diagnosis of fetal goiter during antenatal care was made by ultrasound and MRI. Congenital hypothyroidism was confirmed by fetal blood sampling that was treated with weekly intra-amniotic injections of L-thyroxin. One fetus was initially treated with four weekly intra-amniotic injections of 200 μgms of L-thyroxin...

We analyzed the thyroglobulin (Tg) gene of 2 unrelated patients with congenital goiter and the Tg gene of 2 siblings with the variant type of adenomatous goiter. The clinical characteristics of the patients with congenital goiter and the variant type of adenomatous goiter were very similar, except for serum Tg levels, which were less than 15 pmol/L in the patients with congenital goiter, but 11...

Congenital goiter is a very uncommon cause of neonatal neck mass. Administration antithyroid drugs or radiation exposure during pregnancy may result in reduced synthesis thyroxine and congenital with without thyroid dysfunction. We report case full term, newborn male baby who had normal functions but was born swelling no apparent abnormalities. Maternal investigations for function tests were fo...

Congenital goiter is considered a rare occurrence, and may be related to hypothyroidism, hyperthyroidism, or euthyroidism. In this report, we describe a case of fetal goiter identified in the 34th gestational week in a 41-year-old secundigravida with normal thyroid functions. A conservative approach was followed; the fetal goiter was monitored via ultrasound, which suggested this was a case of ...

background : iodine deficiency produces the spectrum of iodine deficiency disorders (idds) including endemic goiter, hypothyroidism, cretinism and congenital anomalies. other factors, including goitrogens and micronutrient deficiencies may influence the prevalence and severity of idds and response to iodine supplementation. an ssociation between zinc and goiter has previously been reported. met...