This paper incorporates cones on virtual multipliers of inputs and outputs into DEA analysis. Cone DEA models are developed to generalize the dual of the BCC models as well as congestion models. Input-output data and/or numbers of DMUs for BCC models are inadequate to capture many aspects where judgments, expert opinions, and other external information should be taken into analysis. Cone DEA mo...

Purpose The apoptotic mechanisms responsible for secondary cone death in retinitis pigmentosa (RP) remain largely unknown. The cone-enriched apoptotic protease caspase-7 (Casp7) is thought to be triggered by endoplasmic reticulum (ER) stress and plays a pivotal role in mice deficient in the cone cyclic nucleotide-gated channels, a deficiency that causes achromatopsia in humans and in mice with ...

To investigate how rod signals influence hue perception and how this influence can be incorporated into opponent-color models, we measured the shift of unique-hue loci under dark-adapted conditions compared with cone-plateau conditions. Rod signals produced shifts of all spectral unique hues (blue, green, yellow) but in a pattern that was inconsistent with simple additive combinations of rod an...

Cone phototransduction and survival of cones in the human macula is essential for color vision and for visual acuity. Progressive cone degeneration in age-related macular degeneration, Stargardt disease, and recessive cone dystrophies is a major cause of blindness. Thyroid hormone (TH) signaling, which regulates cell proliferation, differentiation, and apoptosis, plays a central role in cone op...

This paper develops inferential theory for hypothesis testing under general convex cone alternatives for correlated data. Often, interest lies in detecting order among treatment effects, while simultaneously modeling relationships with regression parameters. Incorporating shape or order restrictions in the modeling framework improves the efficiency of statistical methods. While there exists ext...

Introduction: Semaphorin 3A (Sema 3A) is a secreted protein, which plays an integral part in developing the nervous system. It has collapse activity on the growth cone of dorsal root ganglia. After the development of the nervous system, Sema 3A expression decreases. Neuropilin 1 is a membrane receptor of Sema 3A. When semaphorin binds to neuropilin 1, the recruitment of oligodendrocyte precurso...

This study examines the capability of the Relevance Vector Machine (RVM) and Multivariate Adaptive Regression Spline (MARS) for prediction of ultimate capacity of driven piles and drilled shafts. RVM is a sparse method for training generalized linear models, while MARS technique is basically an adaptive piece-wise regression approach. In this paper, pile capacity prediction models are developed...