Background: Methadone maintenance therapy (MMT) is considered as an efficient and effective treatment in management of high risk opioids addiction; although, concomitant use of other drugs may interfere with treatment course and outcome in MMT cases. This study aimed at evaluating patterns of drug use along with methadone based on self reported and urine analysis data in two MMT clinics. Method...

Background: Chronic drug abuse and sexual dysfunction specifically erectile dysfunction may lead drug abusers to seek over-the-counter or non-prescription medications, out of which Sildenafil citrate, sold as the trade name of Viagra® can be considered as a prime and important treatment. Therefore, the research purpose was to draw a comparison and review the role of methamphetamine abuse and si...

conclusions globally, interventions that comprise evidence-based prevention, care and treatment of substance use disorders in young adults are vital to reduce the transmission of hiv infection and promote good clinical outcomes for young adults at-risk for living with hiv. context young adults comprise roughly one-quarter of the global population and are at the developmental stage where persona...

severe adverse drug reactions are an important cause of childhood morbidity and mortality. despite this, few reports in the literature describe it. this study was designed to evaluate the admitted pediatric patients due to adverse drug reactions. this retrospective study was conducted at pediatric ward of besat hospital. the records of hospitalized patients that admitted with diagnosis of adver...

There are few, if any, situations in medicine in which a clinician can predict with certainty an individual’s response to drug therapy. A host of factors can modulate this response: concomitant disease or drug therapy, sex, age, ethnicity, or dysfunction of excretory organs, to name but a few. Even when we correct for changes anticipated by such conditions, however, drug responses remain highly...

OBJECTIVES The aim of the study was to investigate the influence of continued injecting drug use, enrolment in an opiate substitution treatment programme (OSTP), or cessation of injecting drug use on the uptake and course of antiretroviral therapy (ART). Design A prospective observational study of all participants in the Swiss HIV Cohort Study followed between 1997 and 2006 was carried out. M...

Severe adverse drug reactions are an important cause of childhood morbidity and mortality. Despite this, few reports in the literature describe it. This study was designed to evaluate the admitted pediatric patients due to adverse drug reactions. This retrospective study was conducted at Pediatric ward of Besat Hospital. The records of hospitalized patients that admitted with diagnosis of adver...