Deposition of behenic acid (B.A) mono and bilayers onto gold coated surfaces was performed by Langmuir-Blodget dip-casting technique. Surface Plasmon resonance (SPR) and ellipsometry methods were employed for investigation of the monolayer and bilayer films. The adsorption of the biologically important molecule Concanavalin A (Con A) from bulk solution to these monolayers and bilayers as we...

this in vitro study was conducted to evaluate lymphocyte blastogenic and cytokine production by bovine peripheral blood mononuclear cells (pbmcs) stimulated with phytohemagglutinin (pha), pokeweed mitogen (pwm) and concanavalin a (con a) mitogens, by using tetrazolium salt and elisa tests, respectively. the results presented that  interleukin-2 (il-2), il-4, il-5, il-10, il-17 and ifn-γ product...

objective(s): systemic candidiasis is an infection of candida albicans (c. albicans) causing disseminated disease and sepsis, invariably when host defenses are compromised. we investigated the histopathological changes as well as the lymphoproliferative responses and cytokine production of splenic cells after stimulation with concanavalin a (con a) and pokeweed mitogen (pwm) in mice with dissem...

The Immunogenicity of γ-irradiated tachyzoites of a highly virulent strain of Toxoplasma gondii (RH strain) was investigated. Immunized mice survived challenge infection and displayed increased interferon gamma (INF-γ ) production. On the other hand, nonimmunized controls died after 10 days and displayed a significantly decreased lymphoproliferative response to Concanavalin A (Con A). No tachyz...

This in vitro study was conducted to evaluate lymphocyte blastogenic and cytokine production by bovine peripheral blood mononuclear cells (PBMCs) stimulated with phytohemagglutinin (PHA), pokeweed mitogen (PWM) and concanavalin A (Con A) mitogens, by using tetrazolium salt and ELISA tests, respectively. The results presented that  Interleukin-2 (IL-2), IL-4, IL-5, IL-10, IL-17 and IFN-...

Multivalent interactions between carbohydrate-encapsulated gold nanoparticles and Con A are found with high affinity and specificity.

Objective(s): Umbelliprenin is a prenyloxy-coumarin with pharmacologically polyvalent activity. Several studies have shown its anti-inflammatory, anti-tumor, antioxidant, and antigenotoxic activity, and other functions. However, the exact mechanism of action of this compound on the immune response has not yet been shown. Here, we investigated umbelliprenin effects on the predominance of Th1 and...

Objective(s): Systemic candidiasis is an infection of Candida albicans (C. albicans) causing disseminated disease and sepsis, invariably when host defenses are compromised. We investigated the histopathological changes as well as the lymphoproliferative responses and cytokine production of splenic cells after stimulation with Concanavalin A (Con A) and Pokeweed mitogen (PWM) in mice with dissem...

The induction by anti-immunoglobulin of patch and cap formation on mouse lymphocytes was inhibited by the addition of concanavalin A. This effect was reversed by alpha-methyl-D-mannoside, a competitive inhibitor of the binding of concanavalin A. Concanavalin A prevented both patch and cap formation, in contrast to the metabolic inhibitor NaN(3), which prevented only cap formation. This suggests...

the immunogenicity of γ-irradiated tachyzoites of a highly virulent strain of toxoplasma gondii (rh strain) was investigated. immunized mice survived challenge infection and displayed increased interferon gamma (inf-γ ) production. on the other hand, nonimmunized controls died after 10 days and displayed a significantly decreased lymphoproliferative response to concanavalin a (con a). no tachyz...