fibrillin is a large glycoprotein synthesized in the tissues involved in marfan syndrome, and known to be involved in tissue elasticity. the syndrome is corresponded to fbn1 gene and is characterized by cardiovascular, ocular, and skeletal abnormalities. n-terminus of fibrillin 1 binds to microfibril-associated glycoprotein 1 (magp-1) in a calcium-dependent manner. in this study, the amino acid...

in descriptive statistics, there are two computational algorithms for determining the variance s2, of a set of observations : algorithm 1: s2= - , algorithm 2: s2= , where . it is interesting to discuss, which of the above formulas is numerically more trustworthy in machine numbers sets. i this paper, based on total effect of rounding error, we prove that the second algorithm is better than ...

viroids are smallest, single-stranded, circular, highly structured plant pathogenic rnas that do not code for any protein. viroids belong to two families, the avsunviroidae and the pospiviroidae. members of the pospiviroidae family adopt a rod-like secondary structure. in this study the most stable secondary structures of citrus viroid variants that reported from fars province were drawn. the m...

computational tools are reliable alternatives to laborious work in chimeric protein design. in this study, a chimeric antigen was designed using computational techniques for simultaneous detection of anti-htlv-i and anti-hbv in infected sera. databases were searched for amino acid sequences of hbv/hlv-i diagnostic antigens. the immunodominant fragments were selected based on propensity scales. ...

conclusions based on the location of detected rccs in the structure of hbv proteins, it was found that these rccs may have a critical role in correct folding of hbv proteins and can be considered as drug targets. the results of this study provide new and deep perspectives about structure of hbv proteins for further researches and designing new drugs for treatment of hbv. results the pfam search...

background and aim : the hearing loss and acoustic feedback signal in the binaural hearing aids may annoy users, make speech reorganization difficult, and affect the sound quality. this paper presents a new method for acoustic feedback suppression in binaural hearing aids, based on the combination of binaural information and blind source separation. this method can enhance sound from the specif...

in this paper by using concepts of graph theory, forces method and substructure ing method for analysis of structures, some methods have been introduced for optimal analysis of structures in a large scale, using substructuring method. planar rigid frames assuming linear behavior and small deformations, have been optimal analyzed, by using forces method. thus, a fortran power station computation...