compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

a) In mammals, large peripheral nerves, for example the vagus, the sciatic and the ulnar typically are bundles of thousands of individual axons enclosed in a loose connective tissue sheath, the Epineurium. Within the Epineurium, the axons are grouped in fascicles, encased in a more structured epithelial sheath (the perineurium). Each axon is surrounded by a thin connective tissue sheath, the en...

Compound action potential (CAP) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. These properties are measured using amplitude, latency and area under curve of CAPs recorded from spinal cord. Here, the isolated spinal cord was set in a double sucrose gap (DSG) chamber and its response to intracellular stimulation ...

Increased expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNFalpha) and its soluble receptors is evident within the central nervous system (CNS) following traumatic brain injury and spinal cord injury. TNFalpha is integral to the acute inflammatory cascade that follows neurotrauma and has been shown to have both beneficial and detrimental properties. We examined the effe...

The influence of electrical stimulation on the amplitude of the action potentials recorded from the mouse nervous system in vitro was investigated. Brief (1 s) high frequency (100 Hz) stimulation of the sciatic nerve induced a longlasting increase in the amplitude of the compound action potential (CAP). Low frequency (1 Hz) stimulation delivered for 15 min attenuated the antidromically evoked p...

1. The compound action potential (CAP) output from the isolated eye of Aplysia, in darkness at constant temperature, exhibits a circadian rhythm of CAP frequency and a circadian rhythm of CAP amplitude when recorded in culture medium for up to two weeks. 2. Deuterated culture medium lengthened the period of the CAP frequency rhythm linearly from 26-7 h in normal culture medium to 33-7 h in 50% ...

The belief that the cochlea is particularly vulnerable to a reduction in oxygen availability comes predominantly from studies reporting the disruption of electrophysiological measures, such as the compound action potential, endocochlear potential, inner hair cell intracellular potentials or afferent nerve fiber responses by asphyxiation. Because hypoxia has frequently been suggested as an under...

In order to determine possible functional and morphometrical alterations produced by perinatal undernourishment on peripheral nerves, sensory sural nerves from control and undernourished rats of 30 and 90 postnatal days of age were dissected and divided in two segments, one for recording the compound action potential (CAP) and the other for histological examination. Nerves from undernourished a...

Zhang, Si Yi, Donald Robertson, Graeme Yates, and Alan Everett. Role of L-type Ca channels in transmitter release from mammalian inner hair cells. I. Gross sound-evoked potentials. J. Neurophysiol. 82: 3307–3315, 1999. Intracochlear perfusion and gross potential recording of sound-evoked neural and hair cell responses were used to study the site of action of the L-type Ca channel blocker nimodi...