The aim of this study is the evaluation of the e ect of microencapsulation of nanoparticles in composite microparticles on the reduction of burst release. Microparticles (simple and composite) and nanoparticles were prepared by using water-in-oil-in-water (W/O1/W2 double-emulsion solvent di usion/evaporation method), using di erent drug/polymer ratios. For preparation of the composite micropart...

objective(s) theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. it is used both as a prophylactic drug and to prevent acute exacerbations of asthma. the aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. materials and me...

Here, we produce poly(lactide-co-glycolide) (PLGA) based microparticles with varying morphologies, and temperature responsive properties utilizing a Pluronic F127/dextran aqueous two-phase system (ATPS) assisted self-assembly. The PLGA polymer, when emulsified in Pluronic F127/dextran ATPS, forms unique microparticle structures due to ATPS guided-self assembly. Depending on the PLGA concentrati...

A new synthetic methodology to produce polymer-AgNP composite microparticles using scCO 2 is presented. These microparticle possessed long-lived antimicrobial activity and were tested for compatibility in the Laser Sintering 3D printing process.

The marginal fracture toughness of several types of composite resins was determined by means of the rattler test. Microparticle-filled resins showed significantly higher marginal fracture toughness than conventional composites. Posterior restorative composites were intermediate between MFRs and conventional composites. Amalgams were inferior to restorative resins. These data correspond with the...

Reinforcement of both fibrous and particulate materials can improve composite properties for various applications, such as biomedical applications. The alkali-treated kenaf fibers (SiO2, bentonite, CaCO3) microparticles 400 mesh in size reinforce the epoxy matrix hybrid composites. bending impact composites, well their water absorption, are compared. composites were prepared a compression mold ...

In this study, an iron oxide magnetic microparticles and poly(dimethylsiloxane) (MMPs-PDMS) composite material was employed to demonstrate a simple high-strength reversible magnetic bonding method. This paper presents the casting of opaque-view (where optical inspection through the microchannels was impossible) and clear-view (where optical inspection through the microchannel was possible) MMPs...