the topical delivery of non-steroidal anti-inflammatory drugs (nsaids) such as ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. however, it is dif...

A biocompatible microemulsion system comprising of isopropyl myristate (IPM) as oil, tween 80 as a non-ionic surfactant and isobuthanol as co-surfactant was studied experimentally at 298.15 K. The pseudo-ternary phase diagram for the microemulsion system has been delineated at different surfactant to co-surfactant mass ratio of 1:1, 2.4:1 and 4:1. Some physico-chemical properties such as densit...

     The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...

     The topical delivery of non-steroidal anti-inflammatory drugs (NSAIDS) such as Ibuprofen has been explored as a potential method of avoiding the first pass effects and the gastric irritation, which may occur when used orally. Ibuprofen is formulated into many topical preparations to reduce the adverse effects and simultaneously avoid the hepatic first-pass metabolism as well. However, it i...

Selective desorption of (6,5) single-wall carbon nanotubes from hydrogels only occurs at specific co-surfactant ratios. High-purity fractions are obtained at this ratio even with long elution times and different total co-surfactant concentrations. These results suggest that each (n,m) type forms a thermodynamically-stable surfactant structure in the co-surfactant solution, enabling high-fidelit...

the perovskite-type oxides strontium-substituted lanthanum nickelate (lsno) were prepared by a coprecipitation method in the present of octanoic acid as surfactant. the phase composition, morphology,lattice parameters and size of nanoparticles in these materials were characterized through fourier transform infrared spectroscopy (ft-ir), x-ray diffraction (xrd), scanning electron microscopy (sem...

this work aimed to prepare a nanoemulsion preparation containing budesonide and assess its aerodynamic behavior in comparison with suspension of budesonide. in-vitro aerodynamic performance of the corresponding micellar solution (ie. nanoemulsion preparation without oil) was investigated too. nanoemulsions of almond oil containing budesonide, as a hydrophobic model drug molecule, were prepared ...

Influence of hydrophobic chain lengths of surfactant, co-surfactant, oil and different surfactant to co-surfactant ratios on phase behavior of Tween/alcohol/alkane/H2O was investigated with pseudo-ternary phase diagrams. The total areas of the microemulsion (ME) regions were determined. The largest ME region was formed when the ratio of surfactant: co-surfactant was 2 : 1 (w/w). The capacity fo...

The aim of this study was to develop a microemulsion system as a medium for laccase-catalyzed reactions. Phase behavior studies were conducted by constructing partial pseudo-ternary phase diagrams for systems comprising of cetyltrimethylammonium bromide (CTAB), various organic solvents as the oil phase (i.e., hexane, cyclohexane, heptane, octane, isooctane, toluene, isopropyl myristate), two co...