نتایج جستجو برای: Co-amoxiclav

تعداد نتایج: 333054  

Journal: :The Journal of antimicrobial chemotherapy 2003
Javier Garau Monique Twynholm Elena Garcia-Mendez Bartolome Siquier Antonio Rivero

OBJECTIVES Pharmacokinetically enhanced co-amoxiclav 2000/125 mg was designed to achieve high serum concentrations of amoxicillin over the 12 h dosing interval to eradicate Streptococcus pneumoniae with amoxicillin MICs of at least 4 mg/L. METHODS This randomized, double-blind, double-dummy, multicentre study compared the efficacy and safety of oral co-amoxiclav 2000/125 mg twice daily versus...

2002
Véronique Leflon-Guibout Géraldine Ternat Beate Heym Marie-Hélène Nicolas-Chanoine

Co-amoxiclav is widely used in France to treat different infectious diseases, in particular community-acquired otitis, sinusitis and pneumonia, and occasionally urinary tract infections (UTIs). While the mechanisms of resistance to co-amoxiclav have been well defined, particularly in Escherchia coli, the influence of co-amoxiclav treatment on the in vivo selection of E. coli resistant to co-amo...

2017
Monia Donati Domenico Motola Roberto Leone Ugo Moretti Giovanna Stoppa Elena Arzenton Maria Carmela Lenti Roberto Bonaiuti Alessandro Mugelli Alfredo Vannacci Concetta Rafaniello Liberata Sportiello Annalisa Capuano Oscar Bortolami Alberto Vaccheri

Objective: Several studies showed that amoxicillin plus clavulanic acid (co-amoxiclav) is one of the most common agents associated to serious Drug Induced Liver Injury (DILI). We estimated the risk of acute serious DILI associated with amoxicillin alone compared with co-amoxiclav, through a multicenter case-control study carried out in nine Italian hospitals from October 2010 to January 2014. M...

Journal: :Rocky Mountain medical journal 1966
G S Richardson

A total of 389 children (age 0.6-10.2 years) with typical signs and symptoms of acute otitis media were randomized (1:1) to treatment with either azithromycin or co-amoxiclav. The dosage schedule for azithromycin was 10 mg/kg/day, in a single daily dose, administered for three days. Co-amoxiclav was given at a dose of 13.3 mg/kg (amoxycillin equivalent) tid for ten days. Patients were evaluated...

2010
Maryam Amini Mohammadebrahim Yarmohammadi Pupak Izadi

Background: Chronic sinusitis is one of the most common medical problems affecting 30 million people in USA annually. In the present study, we compared the efficacy and safety of clarithromycin XL and co-amoxiclav on clinical and CT scan findings of patients suffering from chronic sinusitis. Patients and methods: In this clinical trial, a total of 59 subjects (37 males and 22 females, mean age ...

Journal: :The Journal of antimicrobial chemotherapy 2003
Michael W Dunne Thomas Latiolais Barnett Lewis Bruce Pistorius Gerald Bottenfield William H Moore Anne Garrett Tracy D Stewart Jeffrey Aoki Craig Spiegel David Boettger Anne Shemer

BACKGROUND Compared with 5 days of dosing, a 3 day dosing regimen of azithromycin for treatment of acute otitis media (AOM) may improve compliance, will simplify therapy for the caregiver and, by giving the same total dose as the 5 day regimen, provide more drug when the bacterial burden is highest. METHODS Children of 6 months-12 years were enrolled if they had had symptoms and signs of AOM ...

Journal: :The Journal of antimicrobial chemotherapy 2004
Pauliina Kärpänoja Antti Nissinen Pentti Huovinen Hannu Sarkkinen

OBJECTIVES The objective of this multicentre study was to define the accuracy and reproducibility of the NCCLS disc diffusion method for Haemophilus influenzae against ampicillin and co-amoxiclav in Finnish clinical microbiology laboratories. Special attention was paid to the ability of the laboratories to detect beta-lactamase-negative ampicillin-resistant (BLNAR) strains. METHODS Three BLNA...

Background and Aims: Hepatotoxicity induced by Co-amoxiclav has been indicated in multiple studies. Thymol is the main constituent of the Thymus vulgaris essential oil that has antioxidant properties. Even though thymol can exhibit antioxidant activity in vivo models, there is a lack of evidence about the thymol’s effectiveness in drug-induced liver injury. Thus, the present study was conducted...

Journal: :Current medical research and opinion 2008
Monique Martin Lee Moore Sibilia Quilici Marc Decramer Steven Simoens

OBJECTIVE This article assesses the cost-effectiveness of outpatient antimicrobial treatment of community-acquired pneumonia (CAP) taking into account resistance in Belgium. RESEARCH DESIGN AND METHODS Our decision analytic model focused on mild to moderate CAP, but did not consider severe CAP. Treatment pathways reflected empirical treatment initiated in the absence of data on CAP aetiology....

2016
L. S. El-Hosseiny N. N. Alqurashy S. A. Sheweita

Clinical studies have shown that several classes of antibiotics are evidenced in drug induced liver injury. The combination of amoxicillin with clavulanic acid is commonly cited in such cases. Accordingly, the present study investigated the potential hepatoprotective and in vivo antioxidant efficacy of sage essential oil in Co-amoxiclav induced hepatotoxicity in rats. Sage essential oil was hyd...

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