Eighteen laboratories participated in a collaborative study on the determination of clopidol residues in chicken muscle tissues by liquid chromatography. Of these, results from 16 laboratories which rigorously followed the method were subjected to statistical analysis. The method performance was assessed by all participants using 14 samples of chicken muscle fortified at concentrations ranging ...

Four veterinary drugs of dissimilar chemical structures were evaluated for environmental stability and penchant for bioaccumulation. The techniques used were (1) a model aquatic ecosystem (3 days) and (2) a model feedlot ecosystem (33 days) in which the drugs were introduced via the excreta of chicks or mice. The model feedlot ecosystem was supported by metabolism cage studies to determine the ...

The different factors (environmental, microbial contamination, handling procedures with game, post mortal changes of game meat) influenced on safety and quality of farmed and hunted wild game meat are described. The emphasis is given on residues of contaminants: risk chemical elements (Cd, Pb, Hg), mycotoxins (aflatoxin, ochratoxin, trichothecene), veterinary drug residues (sulfanilamid, amprol...

Background: Coccidiosis is recognized as the parasitic disease that has the greatest economic impact on poultry production. Modern poultry production is largely dependent upon anticoccidials. Objectives: The aim of the present study was to determine and compare the efficacy of two chemical anticoccidials (Clopidol and Diclazuril) on oocyst shedding and their probable effects on growth performan...

A selective, sensitive gas chromatography-mass spectrometry (GC-MS) method with negative chemical ionization (NCI) was developed for the detection and quantification of clopidol in chicken muscle. Chicken muscle samples were extracted with acetonitrile and concentrated to dryness; the residue was redissolved in ethyl acetate and applied to an Alumina B cartridge for cleanup. The residue was der...

background: coccidiosis is recognized as the parasitic disease that has the greatest economic impact on poultry production. modern poultry production is largely dependent upon anticoccidials. objectives: the aim of the present study was to determine and compare the efficacy of two chemical anticoccidials (clopidol and diclazuril) on oocyst shedding and their probable effects on growth performan...

Anticoccidial drugs were evaluated for activity and for the development of resistance in a model of Toxoplasma gondii growing in human fibroblast cultures. Of 13 anticoccidial drugs tested, 9 had selective antitoxoplasma activity (50% inhibitory concentration, in micrograms per milliliter): decoquinate (0.005), arprinocid-N-oxide (0.015), robenidine (0.03), the aryl triazine CP-25,415 (0.2), to...