purpose: today considerable advances have been achieved in application of nano-particles.   fullerene is one of the artificial forms of carbon element. long life cycle of medicines in the   human body is a success factor in delivery of medicine to the specific place. lots of nanoparticles   are being developed in this field and from a medical point of view, achieving such   goals is vital. the ...

  Purpose: Today considerable advances have been achieved in application of nano-particles.   Fullerene is one of the artificial forms of carbon element. Long life cycle of medicines in the   human body is a success factor in delivery of medicine to the specific place. Lots of nanoparticles   are being developed in this field and from a medical point of view, achieving such   goals is vital. Th...

In this study, the influence of fullerene junction on the chemical features of 16 different drugs including Captopril, Clonidine, Methyldopa, Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylometazoline, Tolazoline, Clemastine, Procyclidine, Tyramine, Nicotine, Dextroamphetamine, Fluoxetine, Metoprolol and Enalapril was investigated computationally. For this purpose, the mentioned drugs were pl...

In this study, the influence of fullerene junction on the chemical features of 16 different drugs including Captopril, Clonidine, Methyldopa, Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylometazoline, Tolazoline, Clemastine, Procyclidine, Tyramine, Nicotine, Dextroamphetamine, Fluoxetine, Metoprolol and Enalapril was investigated computationally. For this purpose, the mentioned drugs were pl...

Clonidine has two aromatic rings in which halogens are attached to one ring in this study, both in drug state and in fullerene nanostructure, and by changing the type of halogen at the * HF / 6-31G level and in The gas phase was first optimized and then the NBO calculations were performed. The results obtained in N61, N63 and N5, N3 indicate the highest rhizanese energy and load transfer that, ...

clonidine has sedative and analgesic properties. randomized studies examining these properties in mechanically ventilated icu patients are scarce. this study was designed to assess the impact of clonidine on sedative agent use in mechanically ventilated patients.in a prospective, randomized, double blind, placebo-controlled study in a general icu of a university medical center in tehran, iran, ...

clonidine hydrochloride is an antihypertensive agent used for migraine prophylaxis, attention deficit hyperactivity disorder, menopausal flushing and tourette syndrome. the quantity of the active substance in pharmaceutical preparations must be within specific limits, in agreement with the respective label claim. therefore, the aim of this study was to establish the conditions for two spectroph...

Clonidine has sedative and analgesic properties. Randomized studies examining these properties in mechanically ventilated ICU patients are scarce. This study was designed to assess the impact of clonidine on sedative agent use in mechanically ventilated patients.In a prospective, randomized, double blind, placebo-controlled study in a general ICU of a university medical center in Tehran, Iran, ...

In this study, the effect of fullerene electron mobility on the composition of paraphenylenediamine and stability was studied. Using quantum chemistry calculations, the first combination of paraffenylenediamine in a single-full-time region connected with fullerene through carbon atoms was reported. Experimental research was simulated and optimized using GIS software. Then the NBO calculations w...