evidence based medicine is very important for success of modern medicine. it is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. it not only identifi...

introduction: performing correct research in different aspects of community as well as medical sciences can be a way to resolve many problems. in order to create a systematic knowledge of research method in academic members of arak university of medical sciences and enabling them in providing proposals and performing researches, a clinical research center was developed. this study is done to in...

purpose: to compare the outcomes of deep anterior lamellar keratoplasty (dalk) using the big-bubble technique with that of penetrating keratoplasty (pk) in patients with keratoconus. methods: this double-blind clinical trial included patients with moderate to advanced keratoconus and poor spectacle-corrected visual acuity or contact lens intolerance. refractive errors, best corrected visual acu...

objective: glutamate antagonists including anticonvulsant topiramate have been recommended for the pharmacological management of schizophrenia. methods: a randomized, double-blind, placebo controlled clinical trial was performed on 32 patients diagnosed with schizophrenia (18-45 years old). baseline information was gathered on demographic characteristics, vital signs, height, weight, smoking ha...

introduction: the purpose of this article was to evaluate the quality of sample size calculation reports in published clinical trials in journal of endodontics and international endodontic journal in years 2000-1 and 2009-10. materials and methods: articles fulfilling the inclusion criteria were collected. the criteria were: publication year, research design, types of control group, reporting s...

background: infantile colic, cry-fuss and sleep problems are transient in the initial months of life, but they contribute to maternal depression, parenting stress and family mental health problems. in this randomized clinical trial, we aimed to explore the efficacy of massage therapy compared to rocking in reducing infantile colic symptoms including duration and number of cries, sleep duration ...

background: degenerative joint disease (djd) is the most common joint disease in human beings. previous studies have explained that glucosamine is preferred as placebo and in efficacy compared with nsaid’s in treatment of patients’ knee osteoarthritis. alendronate was used to treat osteoporotic patients and its efficacy was established. objectives: the aim of this study was to compare the effic...

attention-deficit/hyperactivity disorder is one of the most common mental disorders in childhood, and it continues to adulthood without proper treatment. stimulants have been used in the treatment of attention-deficit/hyperactivity disorder (adhd) for many years, and the efficacy of methylphenidate in the treatment of adults with adhd has been proven to be acceptable according to meta-analysis ...