background thyroid dysfunction is the second most common endocrine disease in females of reproductive age. there are controversial data on the adverse effect of subclinical thyroid dysfunctions on adverse feto-maternal outcomes. objectives the current study aimed to identify the prevalence of thyroid dysfunction during pregnancy and to assess the effectiveness of treatment with levothyroxine on...

background: intrauterine insemination (iui) is one of the most appropriate and cost-effective methods in infertility treatment. objective: we aimed to investigate effect of vaginal misoprostol on pregnancy rate after iui. materials and methods: two hundred and ten infertile women who were referred to infertility clinic of alzahra hospital by an indication of iui during 2012-2013 were randomly a...

hydrosalpins (dilatation of fallpian tube that can be seen by hysterosalpingogeraphy. laparoscocpy, and in severe cases by sonography) is one of the probable confounding factors of assited – reproduction therapy (art) outcomes. this cohort study is conducted to determine the effects of hydrosalpins on ivf-et outcomes. for this, of the total number of patients who had approached the infertility ...

background: this study intended to determine the effects of vitamin d and calcium?vitamin d in treating leg cramps in pregnant women. materials and methods: this study was conducted as a double?blind randomized controlled clinical trial on 126 participants, 18–35?year?old pregnant women with a minimum of two leg cramps per week who were referred to health?care centers in tabriz?iran in 2013. th...

objective: repeated implantation failure (rif) is a condition in which the embryos implantation decreases in the endometrium. so, our aim was to evaluate the effect of local endometrial injury on embryo transfer results. materials and methods: in this simple randomized clinical trial (rct), a total of 120 patients were selected. the participants were less than 40 years old, and they are in thei...

background: routine use of assisted hatching (ah) following icsi is a controversial issue in the literature. there are rare studies regarding the effect of laser assisted hatching (lah) on live birth rate. objective: our main goal was to evaluate the effect of lah on delivery rate as well as congenital anomaly in patients undergoing their first icsi cycle. materials and methods: a total of 182 ...

background :subclinical hypothyroidism may adversely affect in vitro fertilization (ivf) outcomes. however the cutoff of thyroid-stimulating hormone (tsh) for diagnosis and treatment is controversal. the aim of this study was to find the association of clinical pregnancy rate with regard to tsh levels in women undergoing ivf.   methods: a historical cohort study of 816 infertile patients who un...

background: the selection of blastocyst warmed for transfer is based on pre-freeze morphology in vitrified-warmed single blastocyst transfer cycles. but, it is controversial which parameter of blastocyst morphology most closely related to the clinical outcomes. objective: to estimate the effect of blastocoele expansion, trophectoderm (te) morphology grade, and inner cell mass (icm) morphology g...

background: polycystic ovary syndrome (pcos) is a common cause of ovulatory disorders and infertility with high lh to fsh ratio. in order to prevent further increase of lh and follicle atresia, different regimens for ovulation induction have been recommended using fsh alone.   objective: this study was performed in pcos patients to compare art outcomes in cycles induced by fsh alone, using eith...

the success of oocyte donation is influenced by multiple factors. we performed a retrospective analysis to evaluate prognostic factors in oocyte donation cycles. the main outcome measurements including recipient age, donor age, estradiol level in midcycle, the day of transfer and number of transferred embryos were not different in pregnant and non pregnant groups. endometrial pattern but not en...