نتایج جستجو برای: Cleavage
تعداد نتایج: 47135 فیلتر نتایج به سال:
افزایش dna به محلول لیگاند شیف باز موجب کاهش شدت جذب در اسپکتروفتومتری لیگاند ، افزایش ویسکوزیته محلول، افزایش در طیفهای فلورسنس و تغییرات کانفورماسیونی شدید در طیف دورنگ نمایی چرخشی dna شده است. این نتایج نشان دادند که این لیگاند شیف باز میتواند به طریق intercalation با dna برهمکنش بدهد. نتایج ژل الکتروفورز نیز نشان دادند که این لیگاند قادر به ایجاد cleavage در puc 18 plasmid dna می باشد. ا...
Due to its artificial and unnatural structure, Israeli society has since the beginning of its establishment, been a context for the emergence of different kinds of cleavages and tensions. This state of affairs has endangered the political stability of the Israeli regime. The present research is trying to answer this question: what is the effect of religious-secular cleavages in Israel on the fu...
Background and Aims: The caspases are unique proteases that mediate the host cell apoptosis during viral infection. In this study, we identified the caspase cleavage motifs of H5N1 and H9N2 influenza viruses isolated during 1998-2012. Materials and Methods: Amino acid sequences of the eleven proteins encoded by the viruses as the caspase substrates downloaded from NCBI. The caspase cleavage mot...
introduction: pronuclear size, morphology and orientation are known to affect embryo quality and implantation. the present study was aimed at evaluation of the possible relationship between protamine deficiency with pronuclear morphology and also cleavage and embryo quality. material and methods: semen sample of 160 candidate icsi and ivf couples were analyzed for sperm concentration, and motil...
The cleavage stimulation factor (CstF) is essential for the first step of poly(A) tail formation at the 3' ends of mRNAs. This heterotrimeric complex is built around the 77-kDa protein bridging both CstF-64 and CstF-50 subunits. We have solved the crystal structure of the 77-kDa protein from Encephalitozoon cuniculi at a resolution of 2 A. The structure folds around 11 Half-a-TPR repeats defini...
introduction : activated protein c (apc) inactivates factor v by cleavage of its heavy chain at arg306, arg506, arg679, and lys994. mutational changes, which abolish apc cleavage sites, may predispose thrombosis by altering the inactivation process of factor v. factor v leiden (arg506glu) has been demonstrated as a strong risk factor for thrombosis. in the current study, we have studied whethe...
It is well established that many metal ions accelerate the spontaneous degradation of RNA. This property has been exploited in several ways to garner information about RNA structure, especially in regards to the location of site-specifically bound metal ions, the presence of defined structural motifs, and the occurrence of conformational changes in structured RNAs. In this chapter, we review th...
introduction: the value of embryonic stem-like cells in cloning is obvious. production of cloned animals can be achieved by introduction of these cells into a tetraploid embryo. tetraploid embryo is used as a feeder for development of embryonic stem-like cells and can be produced in vitro by electro-fusion of 2-cell embryos. the aim of this study was to ass,essthe effect of voltage alteration a...
the aim of this study was to examine the possible morphological and morphometric changes resulting from vitrification of embryos at the cleavage stage. in this study, 30 mice early-cleavage embryos at different stages of cleavage, resulting from in vitro fertilization (ivf) techniques, were examined before and after vitrification. digital images were taken from embryos before and after vitrific...
Most of the small ribozymes, including those that have been investigated as potential therapeutic agents, appear to be rather poor catalysts. These RNAs use an internal phosphoester transfer mechanism to catalyze site-specific RNA cleavage with apparent cleavage rate constants typically <2 min(-1). We have identified variants of one of these, the Neurospora Varkud satellite ribozyme, that self-...
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