Background and Aims: Co-infection of hepatitis E virus (HEV) in chronic hepatitis C virus (HCV) infected patients can develop and increase liver disease and hepatic complications in the world. The purpose of this study was to assess the prevalence of HEV infection in patients suffering from chronic HCV infection. Materials and Methods: Cross-sectional study testing anti-HEV antibodies in serum...

background: nowadays, the immune response to hepatitis c (hcv) treatment has become a crucial issue mostly due to the interleukin 28b (il-28b) polymorphism effects in chronic hcv patients. the aim of this study was to detect the polymorphism of il-28b gene (rs12979860) in hcv genotype 1 patients treated with pegylated interferon and ribavirin. methods: from the 2010 to 2012, a total of 115 peri...

Background and Aims: The hepatitis C virus (HCV) F protein is a recently described, frameshift product of HCV core encoding sequence. Its function and antigenic properties are unknown. In order to assess the presence of antibodies specific for F protein we characterized specific anti-F antibodies in patients with chronic HCV infection. Methods: The F protein was cloned from the HCV genome....

chronic hepatitis c might lead to several immunological dysfunctions. studies have shown a positive association between hepatitis c virus (hcv) infection and psoriasis. these results suggest that the infection may be one of the triggering factors for the development or exacerbation of psoriasis. here, we present a case of chronic hcv infection with psoriasis who developed exacerbation of skin l...

conclusions this study found that gbv-c infection has a high frequency among injecting drug users with hiv/hcv coinfection and hcv mono-infection in yunnan, china. in patients with chronic hepatitis c and hiv coinfection, gbv-c rna was associated with significantly lower alt and ast levels, suggesting a beneficial effect of gbv-c infection on chronic hepatitis c. results gbv-c rna was identifie...

Background and Aims: Chronic hepatitis C is one of the most important etiologies of cirrhosis and hepatocellular carcinoma worldwide. Clinical condition of hepatic patients and the outcome of chemotherapy are under impact of Hepatitis C virus (HCV) genotypes. Therefore, HCV genotyping is important for prediction of success of chemotherapy and progression of liver diseases. Methods: In thi...

Background and Aims: Hepatitis C virus is one of the viral infections which is mainly transmitted by blood transfusion. Patients with thalassaemia frequently need blood transfusion and are in danger of HCV infection. In most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. Liver is the main site of HC...

Chronic hepatitis C virus (HCV) infection is estimated to affect 57 million people globally.1 Despite the availability of safe and effective pan-genotypic direct acting antivirals,2-5 many countries have yet achieve WHO goal HCV elimination by 2030.1