Chondrosarcoma of the nasal septum is a very rare malignant tumor in head and neck region. To diagnose chondrosarcoma, it challenging to obtain an exact initial impression just by simple physical examination. Therefore, imaging studies are useful assessment chondrosarcoma. Pathological confirmation necessary for definitive diagnosis In treatment complete surgical resection most effective, but o...

chondrosarcoma is the second most common primary mesenchymal malignant tumor of the bone. the most common form is central chondrosarcoma and the rarest is intracortical chondrosarcoma. here, we describe the clinical, pathological, and imaging features of a case of intracortical chondrosarcoma as well as the outcome of surgical treatment. this is the third case reported in the literature.

Chondrosarcoma is a rare malignant cartilage forming tumour usually arising from long bones and rarely seen in cranium. In cranium it is seen to commonly arises from skull base with skull vault being a highly unusual site. We report a case of a 30-year female presenting with complaints of headache for 6 months found to have a large chondrosarcoma in right fronto-parietal region which is an extr...

Osteochondroma is the most common form of benign bone tumors. Chondrosarcoma a rare malignant tumor that may be primary or secondary. We report case 19-year-old man with low grade chondrosarcoma secondary to transformation osteochondroma right distal femur. Here we discuss osteochondroma, chances malignancy chondrosarcoma, work up done in our case, histopathological features differentiate from ...

BACKGROUND Metastasis-associated lung adenocarcinoma transcript 1 (MALAT-1) is identified to be overexpressed in several cancers. However, the role of MALAT-1 in chondrosarcoma is poorly understood. METHODS The expression of MALAT-1 and Notch-1 signaling pathway was detected in chondrosarcoma tissues and chondrosarcoma cells by quantitative real-time polymerase chain reaction (qRT-PCR) and We...

BACKGROUND Although the diagnosis of chondrosarcoma, especially the distinction between enchondroma and low-grade chondrosarcoma or low-grade chondrosarcoma and high-grade chondrosarcoma, is pathologically difficult, differential diagnosis is very important because the treatment strategies for these diseases are completely different. The grading system is crucial in predicting biologic behavior...

Accumulating evidence indicates that dysregulation of miRNAs could contribute to tumor growth and metastasis of chondrosarcoma by infuencing cell proliferation and invasion. In the current study, we are interested to examine the role of miRNAs in the carcinogenesis and progression of chondrosarcoma. Here, using comparative miRNA profiling of tissues and cells of chondrosarcoma and cartilage, we...

BACKGROUND In addition to treating acute promyelocytic leukemia, arsenic trioxide (ATO) suppresses other solid tumors, including chondrosarcoma. However, the effects of ATO on metastasis in chondrosarcoma cells, and the underlying molecular mechanisms remain unclear. METHODS The effects of ATO on the migratory and invasive capacities of chondrosarcoma cells were investigated by Wound healing,...

Chondrosarcoma is a malignant cartilage-forming cancer composed of cells derived from transformed cells that produce cartilage. Conventional chemotherapy and radiotherapy have very limited efficacy in patients with advanced chondrosarcoma. In the present study, we reported a novel therapeutic approach in the treatment of chondrosarcoma cells. We detected that lactate dehydrogenase-A (LDHA) is h...

Chondrosarcoma of the bone is second most common malignant bone tumor next only to osteosarcoma. The most common type of chondrosarcoma is the conventional chondrosarcoma (90%). The myxoid variant is a rare occurrence and is associated with a worse outcome as opposed to conventional type. There are only a few references of this tumor in literature. The most common location for skeletal myxoid c...