the purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. a total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. the amounts of glucosamine and chondroiti...

The purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. A total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. The amounts of glucosamine and chondroiti...

The purpose of this report is to present the results of analysis of actual glucosamine and/or chondroitin contents of several such products in the market place and to determine if they significantly deviate from their label claim. A total of fourteen products containing glucosamine sulfate and nine products containing chondroitin sulfate were evaluated. The amounts of glucosamine and chondroiti...

   The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...

   The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...

Chondroitin sulfate (CS) is widely used across the world as a nutraceutical and pharmaceutical. Its high demand potential limitations in current methods of extraction call for an alternative method production. This review highlights glycosaminoglycan’s structure, its medical significance, animal source, disadvantages process. We cover production strategies CS precursor, chondroitin. highlight c...

With the use of purified chondroitinase of Proteus vulgaris, a method has been devised for the determination of relative amounts of chondroitin, chondroitin-4-SO*, and chondroitin6-SO4 in cartilage. This method was applied to the analysis of embryonic chick epiphyseal cartilage. With 35S04 and ‘*C-acetate it was possible to study the relationship of embryo age to rate of formation of chondroiti...

Chondroitin sulfate is a major component of the extracellular matrix in both the central and peripheral nervous systems. Chondroitin sulfate is upregulated at injury, thus methods to promote neurite extension through chondroitin sulfate-rich matrices and synthetic scaffolds are needed. We describe the use of both chondroitin sulfate and a novel chondroitin sulfate-binding peptide to control the...

Three species of colonic bacteria can ferment the mucopolysaccharide chondroitin sulfate: Bacteroides ovatus, Bacteroides sp. strain 3452A (an unnamed DNA homology group), and B. thetaiotaomicron. Proteins associated with the utilization of chondroitin sulfate by B. thetaiotaomicron have been characterized previously. In this report we compare chondroitin lyases and chondroitin sulfate-associat...

We identified a novel human chondroitin N-acetylgalactosaminyltransferase, designated chondroitin GalNAcT-2 after a BLAST analysis of the GenBank(TM) data base using the sequence of a previously described human chondroitin N-acetylgalactosaminyltransferase (chondroitin GalNAcT-1) as a probe. The new cDNA sequence contained an open reading frame encoding a protein of 542 amino acids with a type ...