نتایج جستجو برای: Cholinesterase Inhibitors

تعداد نتایج: 191405  

Journal: :iranian journal of psychiatry 0
nazir hashemi abad department of psychiatry, faculty of medicine, yasouj university of medical science, yasouj, iran najafi shala doulatabad department of nursing, college of nursing & midwifery, yasouj university of medical science, yasouj, iran ali mohammadi department of psychiatry, faculty of medicine,yasouj university of medical science, yasouj, iran hamid reza ghafarian srazi department of social medicine, faculty of medicine; yasouj university of medical sciences, yasouj, iran department of epidemiology and biostatistics, tehran university of medical sciences, school of public health, tehran, iran

schizophrenia and various neurological disorders have some signs and symptoms. visual hallucinations are one of such disorders. the related studies in some diseases for example parkinson disease and lewy body dementia indicate that acetylcholine (ach) plays a significant role in neuropsychiatric manifestation and its association with visual hallucination; therefore, visual hallucinations occur ...

Atta-ur-Rahaman Zaheer-ul-Haq A Khalid F Feroz M Iqbal Choudhary S Anjum

The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...

Atta-ur-Rahaman Zaheer-ul-Haq A Khalid F Feroz M Iqbal Choudhary S Anjum

The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...

Journal: :iranian journal of pharmaceutical research 0
ali asghar zarei department of physiology, school of medicine, shahid beheshti university of medical sciences, tehran, iran. seyyed abbas foroutan neuroscience research center, shahid beheshti university of medical sciences, tehran, iran. seyyed mohsen foroutan department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences , tehran, iran. abbas erfanian omidvar department of medical engineering , school of electrical engineering , iran university of science and technology, tehran, iran.

pyridostigmine bromide (pb) is a reversible cholinesterase inhibitor. the aim of this study was to determine the effect of orally administration of single dose sustained-released tablet of pyridostigmine bromide (pbsr) on the frequency domain indices of heart rate variability (hrv). thirty-two healthy young men were participated in this study. they were divided into 2 groups; the pyridostigmine...

In search of potent cholinesterase inhibitors, we have carried out the synthesis and biologically evaluation of various benzaldehyde based 2,3-dihydroquinazolin-4(1H)-one derivatives. In vitro assay results revealed that all the synthesized compounds showed activity against both enzymes (AChE and BChE) and in few cases, the inhibition activity was even higher than or comp...

2017
Lídia Blanco-Silvente Xavier Castells Marc Saez Maria Antònia Barceló Josep Garre-Olmo Joan Vilalta-Franch Dolors Capellà

Background We investigated the effect of cholinesterase inhibitors on all-cause discontinuation, efficacy and safety, and the effects of study design-, intervention-, and patient-related covariates on the risk-benefit of cholinesterase inhibitors for Alzheimer's disease. Methods A systematic review and meta-analysis of randomized placebo-controlled clinical trials comparing cholinesterase inh...

Journal: :asia pacific journal of medical toxicology 0
mekkattukunnel a. andrews department of medicine, government medical college, thrissur, kerala, india indira madhavan department of medicine, government medical college, thrissur, kerala, india rakesh t. parakadavathu department of medicine, government medical college, thrissur, kerala, india hithesh sanker thottungal sankaranarayanan department of forensic medicine, government medical college, thrissur, kerala, india andrews andrews department of medicine, government medical college, thrissur, kerala, india

background: gastric lavage (gl) is one of the most commonly used decontamination method for cholinergic insecticide ingestion in developing countries despite lack of supporting evidence. this study was designed to evaluate the outcome of patients with cholinergic insecticide poisoning treated with gl in regards to timing and frequency of the procedure. methods: in this prospective observational...

Journal: :Clinical pharmacokinetics 2002
Michael W Jann Kara L Shirley Gary W Small

Cholinesterase inhibitors are the 'first-line' agents in the treatment of Alzheimer's disease. This article presents the latest information on their pharmacokinetic properties and pharmacodynamic activity. Tacrine was the first cholinesterase inhibitor approved by regulatory agencies, followed by donepezil, rivastigmine and recently galantamine. With the exception of low doses of tacrine, the c...

Journal: :Archives of internal medicine 2005
Sudeep S Gill Muhammad Mamdani Gary Naglie David L Streiner Susan E Bronskill Alexander Kopp Kenneth I Shulman Philip E Lee Paula A Rochon

BACKGROUND The prescribing cascade model involves the misinterpretation of an adverse reaction to 1 drug and the subsequent, potentially inappropriate prescription of a second drug. We present a new example of the prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs used to manage urinary incontinence. METHODS A population-based retrospective cohort study was carr...

Journal: :Biological psychiatry 2001
A Maelicke M Samochocki R Jostock A Fehrenbacher J Ludwig E X Albuquerque M Zerlin

Cholinesterase inhibitors are the only approved drug treatment for patients with mild to moderately severe Alzheimer's disease. Interestingly, the clinical potency of these drugs does not correlate well with their activity as cholinesterase inhibitors, nor is their action as short lived as would be expected from purely symptomatic treatment. A few cholinesterase inhibitors, including galantamin...

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