BACKGROUND & AIMS Hepatitis B e antigen (HBeAg) and hepatitis B core antigen (HBcAg) seem to play different roles in the induction and regulation of the antiviral immune response, although the two antigens share all major CD4(+) T-cell epitopes, and these epitopes can be processed from both antigens via the exogenous antigen-presenting pathway. The aim of this study was to test the ability of a...

objective: plasmodium falciparum chloroquine resistance is a major problem in malaria endemic areas. single nucleotide polymorphisms in pfcrt and pfmdr1 genes are known to be associated with chloroquine resistance in some parts of the world. the major goal of the present study was to detect the five single nucleotide polymorphisms in pfmdr1 gene and one single nucleotide polymorphisms in pfcrt ...

Background: Chloroquine is a 4-aminoquinoline derivative. Initially the substance was used as an antimalarial drug, but now chloroquine also to treat connective tissue diseases. It widely drug in rheumatological diseases, especially rheumatoid arthritis and systemic lupus erythematosus. A number of side effects have been reported public literature among patients using this drug. This article re...

A chloroquint napjainkban szisztémás autoimmun kórképek kezelésére használják, szöveti károsodást gátló és immunomoduláns hatása miatt. Ritka, ám súlyos mellékhatása a szernek, hogy restriktív cardiomyopathia-szerű képet okozhat, ami fenotípus hisztológiai kép tekintetében egyaránt Fabry-kór kardiális manifesztációjára emlékeztet. Munkánkban egy 73 éves nőbeteg esetét mutatjuk be, akinek fulmin...

The aim of this work is to prepare and characterize a carbon-clay paste electrode doped with Titanium Oxide (CPEA/TiO2). This used study the electrochemical behavior drugs such as Chloroquin, Azithromycin Hydroxychloroquin. morphological, structural functional characteristics were carried out using X-ray diffraction (XRD), selected area electron (SAED), scanning microscopy (SEM), Fou...

Zusammenfassung Die gleichzeitige Anwendung mehrerer Methoden beim Suizid wird als „kombinierter Suizid“ bezeichnet. Vorgestellt ein Fall, bei dem zunächst alles auf einen mittels Schusswaffe hindeutet. chemisch-toxikologische Analyse ergibt den Nachweis von Benzodiazepinen und einer potenziell letalen Chloroquinkonzentration im Blutserum, was Methode nach Kusch bezeichnet mit Handlungsunfähigk...

Cheilitis granulomatosa is a rare disorder of unknown etiology. The condition produces chronic and persistent swelling of one or both lips. The treatment of cheilitis granulomatosa is usually ineffective. Various forms of treatment have been used with variable success. Here I report a 40-year old woman from suburbs of Ahwaz, with persistent swelling of lower lip from 8 months ago, who had not r...