â  â  b ackground cystic fibrosis (cf) is an autosomal recessive disease caused by a cf trans-membrane regulator (cftr) defect. its prevalence is 1:2500 in caucasians, 1:15300 among african americans and is rare in southâ­east asia. the present study aims to review demographic data, clinical manifestations and laboratory findings of iranian children diagnosed with cf who referred to a childrenâ...

introduction: bronchiectasis is a common problem in children especially under 5 years. early diagnosis of disease and its causes could be useful in early treatment and preventing probable complications. this study aimed at evaluating the cystic fibrosis (cf) in patients with  bronchiectasis. methods: in a cross-sectional study, 374 children with bronchiectasis were studied. the diagnosis was ma...

results abnormal liver function test was detected in cf patients. as well, liver sonogram was abnormal in approximately one-third of the patients. this study showed a higher prevalence of biochemical abnormality in patients with abnormal livers ultrasonography. conclusions noninvasive paraclinical evaluation methods could be recommended in the patients with cf for early detection of silent live...

conclusions the incidence of mbls producing p. aeruginosa in patients with cf was not low. the findings indicate that the identification of drug-resistance patterns in p. aeruginosa and the detection of mbl-producing isolates are important in the prevention and control of infections. background respiratory infections caused by pseudomonas aeruginosa play an important role in the pathogenesis of...

backgroundbronchiectasis is defined by permanent and abnormal widening of the bronchi. although this process occurs in the context of chronic airway infection and inflammation, since there is no accurate estimation of the etiology of the disease. this study aimed to determine the most important cause of bronchiectasis in tehran, iran.materials and methodsin this retrospective cohort study we us...

PURPOSE Acid neutralization during chemical clearance is significantly prolonged in children with cystic fibrosis, compared to symptomatic children without cystic fibrosis. The absence of available reference values impeded identification of abnormal findings within individual patients with and without cystic fibrosis. The present study aimed to test the hypothesis that significantly more childr...

PURPOSE OF REVIEW Nutritional status in cystic fibrosis is important to the health and long-term survival of patients; however, children with cystic fibrosis are not achieving the dietary recommendations or achieving normal growth. This paper reviews current knowledge about behavioral and environmental barriers to dietary adherence in this population. RECENT FINDINGS Children with cystic fibr...

Background Dermatoglyphics could assist in the diagnosis of congenital abnormalities. The aim of this study was to identify the dermatoglyphic patterns (finger print pattern type, total ridge count of each finger, a-b ridge count, and articulotrochanteric distance [ATD angles]) in the parents of cystic fibrosis children. Materials and Methods We recruited 75 parents of children with cystic fibr...

A qualitative diagnosis of infertility requires attention to female and male physical abnormalities, endocrine anomalies and genetic conditions that interfere with reproduction. Many genes are likely to be involved in the complex process of reproduction. Cystic fibrosis (CF) incidence varies in different White people populations (a higher incidence of CF is observed in northern–western European...