introduction: indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the indian subcontinent. the definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.case presentation: an indian origin one and half year old premorbidly normal male child presented with history of gradual di...

how to cite this article: dara n, sayyari aa, imanzadeh f. hepatic encephalopathy: early diagnosis in pediatric patients with cirrhosis. iran j child neurol. 2014 winter; 8(1):1-11. objective as acute liver failure (alf) and chronic liver disease (cirrhosis) continue to increase in prevalence, we will see more cases of hepatic encephalopathy. primary care physician are often the first to suspec...

background: we aimed to determine the frequency of liver copper storage diseases in iranian children with cryptogenic chronic liver disease (cld). materials and methods: one-hundred and twenty children (52 girls, 70 boys; age range: 3 months-14 years) with cld who attended children's medical center in tehran, iran during the years 1997 through 1999, were enrolled. all viral, metabolic and autoi...

Introduction: Indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the Indian subcontinent. The definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.Case presentation: An Indian origin one and half year old premorbidly normal male child presented with history of gradual di...

INTRODUCTION Indian Childhood Cirrhosis is a disease showed in mystery, since its first description in 1000 B.C. as Mukhmandikagrah and more recently by Sen in 1887. It is almost incurable and hence an unfortunately fatal disease. However, the use of Liv.52 in the therapy of Indian Childhood Cirrhosis along with steroid and other institutional treatment has yielded some promising tests to vario...

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Several papers have reported severe liver disease in association with massive hepatic copper accumulation, which do not seem to be either of the recognised copper associated liver diseases, namely Wilson's disease and Indian childhood cirrhosis. A further case is reported in which novel copper kinetic studies were carried out using the stable isotope 65Cu, showing that this patient did not suff...