background and aims : adverse drug reactions (adrs) are one of the major leading causes of death in the world. this study was designed and conducted because of the importance of adverse events in the cancer treatment setting and regarding this issue there is no study exploring adverse reactions of acute hematologic malignancy chemotherapy in iranian population. methods : this was a prospective,...

background : in this study we evaluated the knowledge and practice of patients with breast cancer about complication of chemotherapy referred to chemotherapy ward of nemazee hospital in shiraz, shiraz province, iran, in 2004. methods: forty patients suffering breast cancer and under chemotherapy, were selected with a simple random sampling method. all were interviewed and a questionnaire was co...

patient noncompliance to current tuberculosis (tb) therapy owing to multidrug administration daily leads to treatment failure and emergence of multidrug resistant and extensively drug resistant tb. to avoid the daily dosing, application of nanotechnology is the only viable solution by virtue of sustained release of drugs. other potential advantages of the system include the possibility of selec...

purpose: the aim of the present study was to detect the expression of p-glycoprotein (p-gp) and multi-drug resistance associated protein 1 (mrp1) in retinoblastoma tumors, and analyze the relationship between its expression, the clinico-pathological features and recurrence. methods: p-gp and mrp1 expression in formalin-fixed paraffin-embedded retinoblastoma bearing ocular tissue sections from 2...

An important complication of chemotherapy is thromboembolic events that can occur during treatment course. In this way, Warfarin can be used as an efficient prophylactic agent to prevent these complications. Although bleeding is a common adverse effect of Warfarin, eosinophilia is a rare side effect of this drug. We have reported a 5-year-old boy with Burkitt lymphoma who underwent chemotherapy...

An important complication of chemotherapy is thromboembolic events that can occur during treatment course. In this way, Warfarin can be used as an efficient prophylactic agent to prevent these complications. Although bleeding is a common adverse effect of Warfarin, eosinophilia is a rare side effect of this drug. We have reported a 5-year-old boy with Burkitt lymphoma who underwent chemotherapy...

malaria is a parasitic disease with limited chemotherapy options. chemotherapy options are limited; moreover, drug resistant frequently occurs. the speed of drug development should be faster to overcome the emerging drug resistance. in the current study, a series of quinolone derivatives were subjected to quantitative structure activity relationship to identify the ideal physicochemical charact...

background: determining the optimal and effective scheme for administrating the chemotherapy agents in breast cancer is the main goal of this scientific research. the most important issue here is the amount of drug or radiation administrated in chemotherapy and radiotherapy for increasing patient's survival. this is because in these cases, the therapy not only kills the tumor cells, but also ki...