Bone scintigraphy has some limitations in detecting bone lesions at the time of diagnosis since Tc99m MDP scintigraphy does not trace lesions lacking osteoblastic activity3. Tc99m Sestamibi (MIBI) has been proposed as a potential tracer in patients with multiple myeloma, as its increased uptake in the bone marrow has been reported as an indicator of myeloma activity4. It has been suggested to b...

Biomedical inorganic chemistry is a relative new research field and investigates possible applications of metal containing agents which display biological activities!,2. An important part of these studies deals with compounds that display antitumor properties. The most successful anticancer drug to date containing a transition metal is cisplatin, [Pt(NH3)2Ch]3. The bioactivity of organometallic...

MEDIUM composed of 15 per cent dimethylsulfoxide ( DMSO ) in a 50 per cent solution of plasma has previously been reported to preserve the clot-retracting activity of frozen human platelets stored under liquid nitrogen at -175 C.’ In order to study further the maintenance of platelet “viability” by this technic, the activity of lactic dehydrogenase ( LDH ) was examined before and after freezing...

In the age of stem cell engineering, it is critical to understand how stem cell activity is regulated during regeneration. Hairs are mini-organs that undergo cyclic regeneration throughout adult life,1 and are an important model for organ regeneration. Hair stem cells located in the follicle bulge2 are regulated by the surrounding micro-environment, or niche3. The activation of such stem cells ...

Acute inflammation of joints can lead to the development of chronic arthritis. The nature of agents that sustain the chronic inflammation remains an enigma, although infectious agents such as Rubella virus, Epstein-Barr virus or Chlamydia have been invoked. In most cases in which an inducing agent was sought, none was found.' However, several antigens have been identified that elicit acute arth...

The density functional theory (DFT) calculations at the level of B3LYP/6-31G was carried out on the structure 4(5)-Imidazole-carbaldehyde-N(5)-phenylthiosemicarbazone (ImTPh) in gas phase using Gaussian 03. Dipole moment (Debye), energy of structure formation (HF; kcal/mol) and point group, NMR parameters such as isotropic shielding (σiso) and anisotropic shielding (σaniso), σ11, σ22 and σ33 ob...

The photoactive pigments of the photosynthetic bacteria are believed to be localized in small spherical bodies called chromatophores.1 Biochemical studies2 have shown that chromatophore preparations catalyze a variety of light-dependent reactions (e.g., photophosphorylation of adenosine diphosphate) and they are, therefore, frequently considered to represent the functional equivalent of green p...

Firstly, we would like to congratulate the authors of the article “Training monitoring in judo: comparison between the load intensity planned by the coach and the intensity perceived by the athlete”1 on their initiative to investigate a theme this relevant to the training load control. Additionally, we should state that the conclusion is at first surprising: “...although the training program ha...