background:  intravenous  recombinant  tissue plasminogen  activator  (rt-pa) is an approved  treatment for acute ischemic stroke within 4.5 h of symptoms onset. decompressive craniectomy (dc) has been  shown  as an effective  therapeutic  modality in malignant  middle cerebral  artery (mca) infarction. as rt-pa could result in hemorrhagic  complication during or after any surgery dc may be ass...

traumatic brain injury is a common entity. however cerebral infarction in infants is a rare entity while the diagnosis of this pathology in the pediatric population is usually difficult. the mild head trauma is rarely accompanied by intracranial injury and even less, with cerebral infarction. we herein report the first case of cerebral infarction after a mild brain trauma in a 2-year-old latin-...

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massive cerebral infarction is often accompanied by early death, secondary to brain edema and trans-tentorial herniation. several reports indicate beneficial effects of decompressive craniectomy in this situation, but the efficacy of this procedure is still a matter of debate. a n experimental study in a period of3 years was done on2 3 patients with brain edema due to massive cerebral infarctio...

background: hyperthyroidism as a risk factor for stroke is not conclusive. there are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. this study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. methods: two groups of hyperthyroid (ht) and control euthyroid rats of equal numbers ...

numerous etiologies are responsible for cases of stroke in young adults. this study reviews the causes of two types of stroke (ischemic and intracerebral hemorrhage) in young adults aged 15 to 40years, admitted to our center (a tertiary care center) from 1997 to 2002. the purpose of this study is to determine the relative frequency of causes of stroke in young adults and compare this with publi...

Objective(s): Carthamus tinctorius L. (CT) or saffloweris widely used in traditional Chinese medicine. This study investigated the effects of CT extract (CTE) on ischemia–reperfusion (I/R) brain injury and elucidated the underlying mechanism. Materials and Methods: The I/R model was conducted by occlusion of both common carotid arteries and right middle cerebral artery for 90 min followed by 24...

objective(s): carthamus tinctorius l. (ct) or saffloweris widely used in traditional chinese medicine. this study investigated the effects of ct extract (cte) on ischemia–reperfusion (i/r) brain injury and elucidated the underlying mechanism. materials and methods: the i/r model was conducted by occlusion of both common carotid arteries and right middle cerebral artery for 90 min followed by 24...

conclusions our findings indicate that fullerenol nanoparticles decrease the brain infarction through enhancement of the sod activity during cerebral ischemia-reperfusion injury. results occlusion of mca induced considerable infarction and lesion in ischemic hemispheres of control ischemic rats (527 ± 59 mm3) in accompany with a decrease in the glutathione content (45%), and sod activity (29%) ...

background: central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. our previous work showed that inhibition of angiotensin converting enzyme (ace) activity prior to induction of ischemia protected the brain from severe ischemia/reperfusion (i/r) injuries. this study evaluated the impacts of post-ischemic inhibition of ace, enalapril, on brain inf...