background and objectives: iran owns a rich and prestigious heritage of medicinal herbs but the majority of these plants have not yet undergone chemical, pharmacological and toxicological studies. in the present study some species form northern parts of iran were evaluated for cytotoxicity. methods: sixteen medicinal plants were extracted with methanol and screened for their cytotoxic activitie...

The genus Centaurea with an extensive background in Iranian traditional medicine represents more than 70 species in Iran that some of them are endemic to Iran. A variety of secondary metabolites has been isolated from this genus thus far. Sesquiterpene lactones and flavonoids have been reported as main compounds of C.bruguierana. Methanolic extract and different fractions of the whole fruiting ...

Background and objectives: Iran owns a rich and prestigious heritage of medicinal herbs but the majority of these plants have not yet undergone chemical, pharmacological and toxicological studies. In the present study some species form northern parts of Iran were evaluated for cytotoxicity. Methods: Sixteen medicinal plants were extracted with methanol and screened for their cytotoxic activitie...

in this study, the total 80% of meoh extract and also petroleum ether, chcl3, etoac, n-buoh, and the remaining meoh fractions obtained by solvent-solvent fractionation of the whole flowering samples of centaurea bruguierana (dc.) hand.-mzt. ssp. belangerana (dc.) bornm. (asteraceae), namely “baad-avard”, collected from borazjan in bushehr province (bushehr, iran) were investigated for larvicida...

Background and objectives: Iran owns a rich and prestigious heritage of medicinal herbs but the majority of these plants have not yet undergone chemical, pharmacological and toxicological studies. In the present study some species form northern parts of Iran were evaluated for cytotoxicity. Methods: Sixteen medicinal plants were extracted with methanol and screened for their cytotoxic activitie...

In this study, the total 80% of MeOH extract and also petroleum ether, CHCl3, EtOAc, n-BuOH, and the remaining MeOH fractions obtained by solvent-solvent fractionation of the whole flowering samples of Centaurea bruguierana (DC.) Hand.-Mzt. ssp. belangerana (DC.) Bornm. (Asteraceae), namely "Baad-Avard", collected from Borazjan in Bushehr Province (Bushehr, Iran) were investigated for larvicida...

Centaurea is one of the most important genera within family Asteraceae. An investigation phytochemical composition bruguieriana using Gas-Chromatography coupled to Mass spectrometry (GC-MS) was performed. Antimicrobial activity evaluated minimum inhibitory concentration method (MIC) and validated by molecular docking for major compounds active fraction (1,10-di-epi-cubenol methyl 8-oxooctanoate...