نتایج جستجو برای: Cellular Reprogramming
تعداد نتایج: 449138 فیلتر نتایج به سال:
s:1202:"It is a truly amazing time to developmental biology. During recent decades, three important breakthroughs have been developed: (i) isolation of stem cells from embryo, (ii) animal cloning by nuclear transfer (NT), and (iii) and induced pluripotent stem cells (iPS). Considering these three approaches of "Cellular Reprogramming", it seems that the required elements for cell therapy now ex...
Objective(s): Similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. Reprogramming-related transcription factors, also known as Yamanaka factors (OCT4, SOX2, KLF4, and c-MYC), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. Long non-co...
a:4:{s:10:"Background";s:1707:"Early embryonic development in mammals begins in transcriptional silence with an oocyte-mediated transcriptional reprogramming of parental gametes occurs during a so called across-the-board process of “erase-and-rebuild”. In this process, the parental transcription programs are erased long before (maternal) or soon thereafter (paternal) fertilization to generate a...
objective(s): similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. reprogramming-related transcription factors, also known as yamanaka factors (oct4, sox2, klf4, and c-myc), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. long non-co...
Multiple sclerosis (MS) is one of the most common neuroinflammatory disorders that causes disability in the young adults. In this disease immune-driven demyelination and following that inefficient remyelination occurs. Therapies for this disease are limited, especially those to enhance myelin repair. Cellular reprogramming using defined genetic factors is a way to produce remyelinating Oligoden...
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