نتایج جستجو برای: Cell fate conversion

تعداد نتایج: 1801765  

Journal: :Stem Cell Research & Therapy 2011

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Journal: :modares journal of medical sciences: pathobiology 2013
majid halvaei atefeh solouk nabiollah abolfathi nooshin haghighipour mahnaz eskandari

the provision of an adequate quantity of cells with proper function and purity is one of the main challenges of tissue engineering studies. stem cells, with their self-renewal and differentiation capacity, are considered one of the main cell sources in the field of tissue engineering. previously, the use of chemical factors seemed to be the only possible way for stem cell differentiation. howev...

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Journal: :Cell Research 2017

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Journal: :The Journal of Immunology 2002

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2016
Jaba Gamrekelashvili Roberto Giagnorio Jasmin Jussofie Oliver Soehnlein Johan Duchene Carlos G Briseño Saravana K Ramasamy Kashyap Krishnasamy Anne Limbourg Tamar Kapanadze Chieko Ishifune Rabea Hinkel Freddy Radtke Lothar J Strobl Ursula Zimber-Strobl L Christian Napp Johann Bauersachs Hermann Haller Koji Yasutomo Christian Kupatt Kenneth M Murphy Ralf H Adams Christian Weber Florian P Limbourg

A population of monocytes, known as Ly6C(lo) monocytes, patrol blood vessels by crawling along the vascular endothelium. Here we show that endothelial cells control their origin through Notch signalling. Using combinations of conditional genetic deletion strategies and cell-fate tracking experiments we show that Notch2 regulates conversion of Ly6C(hi) monocytes into Ly6C(lo) monocytes in vivo a...

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Journal: :Cell 2014

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Journal: :journal of research in medical sciences 0
hamidreza aghayan masoud soleimani parisa goodarzi abbas norouzi-javidan seyed hasan emami-razavi bagher larijani

nowadays, scientific c findings in the field of regeneration of nervous system have revealed the possibility of stem cell based therapies for damaged brain tissue related disorders like stroke. furthermore, to achieve desirable outcomes from cellular therapies, one needs to monitor the migration, engraftment, viability, and also functional fate of transplanted stem cells. magnetic resonance ima...

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Journal: :Stem Cells International 2020

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Journal: :Nature 2017

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2016
Behnam Ebrahimi

Forced expression of lineage-specific transcription factors in somatic cells can result in the generation of different cell types in a process named direct reprogramming, bypassing the pluripotent state. However, the introduction of transgenes limits the therapeutic applications of the produced cells. Numerous small-molecules have been introduced in the field of stem cell biology capable of gov...

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