The Catharanthus roseus L. plant leaf extracts were prepared by using solvents such as acetone, ethanol, and chloroform and tested against pathogenic microorganisms to determine their antimicrobial potential. Catharanthus roseus leaf extracts showed maximum antibacterial activity against all the pathogenic microorganisms. Among the solvents tested, ethanol showed maximum antibacterial activity ...

Catharanthus roseus is well known for its pharmacological significance. The present study aims to determine the antifungal activity of Catharanthus roseus against various clinically significant fungal strains (Candida albicans, Aspergillus fumigatus, Aspergillus niger, Fusarium moniliforme). Assessment of antifungal activity of Catharanthus roseus was done by paper disc diffusion method. In thi...

Catharanthus roseus (L.) which is an important medicinal plant of the family Apocynaceae is used to treat many of the fatal diseases contains a virtual cornucopia of useful alkaloids, used in diabetes, blood pressure, asthma, constipation, and cancer and menetrual problem. There are about two common cultivars of C. roseus which is named on the basis of their flower colour that is the pink flowe...

Herbal medicine industry in Indonesia was shaken when Indonesian National Agency of Drugs and Food control prohibits the development of herbal medicines made from Catharanthus roseus. The reason given is that Catharanthus roseus contains alkaloids causing bone marrow depression. The purpose of this article to explore the effects of both preclinical and clinical pharmacological of Catharanthus r...

Changing in the production of anticancer drugs (vinblastine and vincristine) Catharanthus roseus (L.) G. Don by potassium ascorbic acid treatments | Neda Sahi, Akbar Mostajeran, Mustafa Ghanadian Agricultural Journals

Catharanthus roseus (= Vinca rosea), Adenine Phosphori­ bosyltransferase, Subcellular D istribution, Mitochondria, Purine Salvage Subcellular localization of adenine phosphoribosyltrans­ ferase was examined in Catharanthus roseus cells. At least 13% of the activity was observed in the particulate fraction with the rest observed in the cytosol. Both differential and Percoll density gradient cent...

The leaves extract of Catharanthus roseus was investigated for hypotensive and hypolipidemic effects in adrenaline-induced hypertensive rats (AIHR) and compared with those of Atenolol in a crossover design. The pharmacologically Active components responsible for hypotensive activities were isolated from plant using bioassay guided purification approach and the structure of the compounds was pro...

Induced mutagenesis is best approach for creation of genetic variability but most of interest is paid towards crop plants with only a few exceptions. But even widely used medicinal plants could receive a little attention in this direction. Catharanthus roseus is an important plant medicinal plant yielding antihypertensive alkaloid ajmalcine and anticancerous alkaloid vincristine and vinblastine...

BACKGROUND The leaf juice or water decoction of Catharanthus roseus L. (Apocyanaceae) is used as a folk medicine for the treatment of diabetes all over the world. In the present investigation, the leaf juice of C. roseus has been evaluated for its hypoglycemic activity in normal and alloxan-induced diabetic rabbits. METHODS The blood glucose lowering activity of the leaf juice was studied in ...

The anti-oxidant activity and total phenolic content of alcoholic extracts from seven medicinal plants (Asparagus racemosus, Ocimum sanctum, Cassia fistula, Piper betel, Citrus aurantifolia, Catharanthus roseus, and Polyalthia longifolia) were evaluated by using a model system consisting of β-carotene, DPPH free radical and Folin-Ciocalteu method. The total Phenolic content of the extracts was ...