Lead causes damage to the body by inducing oxidative stress. The sites of damage include the bone marrow, where marrow hypoplasia and osteosclerosis may be observed. Leaves of Carica papaya, which have antioxidant and haemopoietic properties, were tested against the effect of lead acetate in experimental rats. The rats were divided into 8 groups; control, lead acetate only, Carica papaya (50 mg...

A preliminary survey of genetic diversity among 34 commercially popular Carica papaya cultivars from India and abroad, 6 accessions of Vasconcellea species and 1 accession of Jacaratia spinosa, was done using 20 simple sequence repeat (SSR) markers. The SSR profiles were used to find out total number of alleles, null and rare alleles, Polymorphism Information Content (PIC) values and to calcula...

BACKGROUND Exposure of animals to xenobiotics may or may not trigger adverse response at cellular levels. Aqueous extract of unripe Carica papaya is consumed by sickle cell patients as antisickling agent in Western Nigeria. AIM This study was undertaken to investigate the effects of Carica papaya on certain organs in Wister albino rats exposed to aqueous extract of unripe Carica papaya. MAT...

The present study was under taken to establish the uterine stimulant activity of aqueous extract of unripe Carica papaya. The effect of the aqueous extract of unripe Carica papaya was studied on isolated rat uterus and embryo. Uterine stimulant activity was compared with clinically available drug oxytocin and the effect on embryo was compared with misoprostol. In the in vitro model, Carica papa...

Carica papaya, belongs to the family of Caricaceae, and several species of Caricaceae have been used as remedy against a variety of diseases[1] Originally derived from the southern part of Mexico, Carica papaya is a perennial plant,and it is presently distributed over the whole tropical area. In particular,Carica papaya fruit circulates widely, and it is accepted as food or as a quasi drug. Man...

Genetic relationships among Carica papaya cultivars, breeding lines, unimproved germplasm, and related species were established using amplified fragment length polymorphism (AFLP) markers. Seventy-one papaya accessions and related species were analyzed with nine EcoRI-MseI primer combinations. A total of 186 informative AFLP markers was generated and analyzed. Cluster analysis suggested limited...

Department of Biochemistry Federal University of Technology, Minna, Nigeria. Corresponding Author: Saidu, A.N ___________________________________________________________________________ Abstract The phytochemical screening and hypoglycemic effect of Carica papaya stem bark in alloxan-induced diabetic albino rats was investigated. Phytochemical analysis of the methanolic extract of Carica papaya...

BACKGROUND Oxidative stress plays a crucial role in the development of drug induced nephrotoxicity. The study aimed to determine the nephroprotective and ameliorative effects of Carica papaya seed extract in paracetamol-induced nephrotoxicity in rats. OBJECTIVES To carry out phytochemical screening of Carica papaya, measure serum urea, creatinine and uric acid and describe the histopathologic...

Purpose: To investigate the interacting effects of co-administration of Carica papaya leaf extract on the hypoglycemic activity of metformin and glimepiride in an animal model. Method: Experimental factorial design was used to evaluate the individual and interaction influence of three variables ie nature (N), dose administered (C) and duration of administration (D), in a 2(=8) employed at two l...

This paper aims at reviewing Carica papaya as potential natural medicinal source. Several studies on methods used in extracting Carica papaya materials from different parts of the plant were highlighted. Extracts from different parts of Carica papaya plant have shown protective effects against many diseases such as intestinal worms infection and different types of wounds. Extracts also showed p...