the reliability of gene expression profiling based technologies and methods to find transcriptional differences representative for the original samples is influenced by the quality of the extracted rna. hence, rna extraction is the first step to investigate the gene expression and its function. consequently, the quality of extracted rna is really significant. correspondingly, this research was ...

abstract background: coherent scattering leads to diffraction effects and especially constructive interferences. theseinterferences carry some information about the molecular structure of the tissue. as breast cancer isthe most widespread cancer in women, this project evaluated the application of small anglex-ray scattering (saxs) for differentiation between normal and cancerous breast tissues....

background: trace elements play an important role in a number of biological processes. astaxanthin (asx), a carotoid pigment found in certain marine plant and animals, has shown anti cancer and anti free radical properties. this work intended to understand the effect of astaxanthin in breast cancer (invasive ductal carcinoma, idc) by using micro-pixe method. for this aim the concentration of tr...

abstractintroduction: cancer is caused by genetic abnormalities, such as mutation of ontogenesis or tumor suppressor genes which alter downstream signaling pathways and protein-protein interactions. comparison of protein interactions in cancerous and normal cells can be of help in mechanisms of disease diagnoses and treatments. methods: we constructed protein interaction networks of cancerous a...

Demonstrated a reliable distinction in the emission and circular dichroism spectral features of TO dye, on binding to DNAs from non-cancerous cancerous tissues, which offers label-free optical method for diagnosis cancer tissues.

Possible effects of aqueous garlic (Allium sativum Linn.) and red clover (Trifolium pratense Linn.) extracts on adenosine deaminase (ADA) activities were investigated in cancerous and non-cancerous human liver tissues and results were compared with those of Fludarabine, a known ADA inhibitor. Ten cancerous and 10 non-cancerous adjacent liver tissues were obtained from patients with metastatic t...

Simultaneous laser induced- breakdown spectroscopy (LIBS) and acoustic response techniques as well as Laser induced fluorescence (LIF) are applied to investigate the abnormal lymph tissues due to Hodgkin disease. The spectral shift in the emissive fluorescence of the cancerous tissues has been observed respect to the normal ones. Regarding LIBS, the concentrations of Ca and Na trace elements ha...

ABSTRACTIntroduction: Cancer is caused by genetic abnormalities, such as mutation of ontogenesis or tumor suppressor genes which alter downstream signaling pathways and protein-protein interactions. Comparison of protein interactions in cancerous and normal cells can be of help in mechanisms of disease diagnoses and treatments. Methods: We constructed protein interaction networks of cancerous a...