background: chemokine receptors have been shown to play an important role in the development and metastatic spread of various malignancies. in this study, the gene expression profile of some key chemokine receptors involved in metastasis has been investigated in esophageal and breast cancer cell lines.   methods: in a descriptive study, gene expression profile of ccr1, ccr6, ccr7, ccr9, cxcr1, ...

today, use of nanotechnology for cancer therapy is an active field of research. early detection, accurate diagnosis, and individual treatment are the aims which cause nanotechnology as an attractive area for research. among metallic nanomaterials, gold nanostructures have unique properties which make them remarkable candidates for biomedical approaches. surface plasmonic resonance (spr) effect ...

background most of the cancer patients may suffer from pain; therefore, music therapy -as a noninvasive method- is sometimes used to help reduce the pain of cancer patients. objective to evaluate the effects of music therapy on pain in some patients with cancer. material and methods this semi-experimental study was performed at urmia teaching hospital in 2011. a total number of 60 patients with...

despite the major advances in conventional forms of treatment (i.e. surgical techniques, radiotherapy and chemotherapy) and improved survival rates, cancer is still the second leading cause of death in developing countries. one major limitation of cytotoxic drugs and radiation in the treatment of cancer patients is their inability to discriminate between malignant and normal tissues. this in tu...

new cancer therapies with novel mechanisms and functions are needed to treat patients with different cancers. virotherapy is a good scenario for such treatment. the advantages of virotherapy include the potential lack of cross resistance with standard therapies and the ability to cause tumor destruction by numerous mechanisms. oncolytic virus not only possesses unique mechanisms of action that ...

several methods have been employed for cancer treatment including surgery, chemotherapy and radiation therapy. today, recent advances in medical science and development of new technologies, have led to the introduction of new methods such as hormone therapy, photodynamic therapy (pdt), treatments using nanoparticles and eventually combinations of lasers and nanoparticles. the unique features of...

objective: this study aimed to examine the effectiveness of metacognitive therapy on decreasing depression in women with breast cancer. a single-case design was employed in this research.  methods: an ab form of single-subject experimental design was used in this study with 3 baselines (every 10 days) before intervention stage and two measurements during intervention stage and one follow-up (af...

introduction: early diagnosis and appropriate treatment is required in esophageal cancer due to its invasive nature. the aim of this study was to evaluate early post-esophagectomy complications in patients with esophageal cancer who received neoadjuvant chemoradiotherapy (nacr).   materials and methods: this randomized clinical trial was carried out between 2009 and 2011. patients with lower-th...