The study evaluates associated health risks of heavy metals in the soil to inhabitants of two mining areas of Nigeria. For so doing, it collects and analyses nine homogenous soil samples for their lead, copper, cadmium, zinc, and chromium levels, using AAS. The samples are then used to calculate health risks to adults and children. For adult population in Agbaja community, the calculated hazard...

The study evaluates associated health risks of heavy metals in the soil to inhabitants of two mining areas of Nigeria. For so doing, it collects and analyses nine homogenous soil samples for their lead, copper, cadmium, zinc, and chromium levels, using AAS. The samples are then used to calculate health risks to adults and children. For adult population in Agbaja community, the calculated hazard...

background: the aim of this study was to determine bioavailability heavy metal concentrations of cu, cd, cr, co and zn and health risk assessment in different types of klang district, selangor (malaysia) urban surface soil using in physiologically based extraction test in vitro human digestion model. methods: a total of 76 urban surface soil was sampled based on seven different types of land us...

The use of Cr(VI) compounds in leather tanning, pigment production and stainless steel welding can pose serious hazards to workers in these industries, since Cr(VI) is a documented human carcinogen.1 Epidemiological studies have shown that occupational exposure to Cr(VI) increases the risk of workers developing cancer of the lung and the sinonasal cavity and many countries limit both water solu...

BACKGROUND Lung cancer is a major health burden causing 160,000 and 1.6 million deaths annually in the United States and worldwide, respectively. METHODS While seeking to identify stable and reproducible biomarkers in noninvasively collected biofluids, we assessed whether previously identified metabolite urinary lung cancer biomarkers, creatine riboside (CR), N-acetylneuraminic acid (NANA), c...

The evaluations of the potential carcinogenicity of metallic chromium and trivalent chromium by several international and national agencies [International Agency for Research on Cancer (IARC), 1990; Agency for Toxic Substances and Disease Registry (ATSDR), 1993; Canadian Environmental Protection Act (CEPA), 1994; United States Environmental Protection Agency (US EPA), 1998; United States Nation...

Calorie restriction (CR) is one of the most potent broadly acting dietary interventions for inducing weight loss and for inhibiting cancer in experimental models. Translation of the mechanistic lessons learned from research on CR to cancer prevention strategies in human beings is important given the high prevalence of excess energy intake, obesity, and metabolic syndrome in many parts of the wo...

Although the carcinogenicity of hexavalent chromium (Cr+6, Cr(VI)) by inhalation has been known for a long time, there has been little evidence regarding the potential for the carcinogenicity and no ability to estimate cancer potency of Cr+6 by ingestion until recently. The release in 2008 of the National Toxicology Program’s (NTP) chronic bioassay of rats and mice exposed to Cr+6 in drinking w...

background: several epidemiological studies conducted on underground miner’s show that exposure to elevated levels of radioactive radon gas is expected to increase the risk of lung cancer. relative risk of lung cancer is almost linear with radon exposure. elevated concentrations of radon are not only reported within mines but also for closed indoor environment of general public houses. measurem...