نتایج جستجو برای: Cams Mechanism
تعداد نتایج: 566402 فیلتر نتایج به سال:
Controlling the occurrence of defects is a major challenge for manufacturing organizations that are seeking to enhance their competitive position in today’s global market. This paper considers the process of screen-printing T-shirts using hydraulic and pneumatic printing machines. Several defects in the output of this printing process have been observed, especially with multi colors printing as...
Inspired by high promise using naturally occurring antimicrobial peptides (AMPs) to treat infections caused by antimicrobial-resistant bacteria, cationic amphiphiles (CAms) were strategically designed as synthetic mimics to overcome associated limitations, including high manufacture cost and low metabolic stability. CAms with facially amphiphilic conformation were expected to demonstrate membra...
Activation of the death receptor Fas has been reported to produce a two-phase intracellular Ca(2+) release response in coronary arterial myocytes (CAMs), which consists of local Ca(2+) bursts via lysosomal transient potential receptor-mucolipin 1 (TRP-ML1) channels and consequent Ca(2+) release from the sarcoplasmic reticulum (SR). The present study was designed to explore the molecular mechani...
The CD38-ADP-ribosylcyclase-mediated Ca(2+) signaling pathway importantly contributes to the vasomotor response in different arteries. Although there is evidence indicating that the activation of CD38-ADP-ribosylcyclase is associated with CD38 internalization, the molecular mechanism mediating CD38 internalization and consequent activation in response to a variety of physiological and pathologi...
Autophagic flux is an important process during autophagy maturation in coronary arterial myocytes (CAMs). Here, we defined the role and molecular mechanism of the motor protein dynein in the regulation of autophagic flux in CAMs. In mouse CAMs, dynein protein is abundantly expressed. Pharmacological or genetic inhibition of dynein activity dramatically enhanced 7-ketocholesterol (7-Ket)-induced...
Xu M, Li X, Walsh SW, Zhang Y, Abais JM, Boini KM, Li PL. Intracellular two-phase Ca release and apoptosis controlled by TRPML1 channel activity in coronary arterial myocytes. Am J Physiol Cell Physiol 304: C458–C466, 2013. First published January 2, 2013; doi:10.1152/ajpcell.00342.2012.—Activation of the death receptor Fas has been reported to produce a two-phase intracellular Ca release respo...
A packet filter is a hardware or software mechanism that can be configured to select packets from a traffic stream based on some criteria. Many research works have been done in the past in the area of classifying packets based on one or more packet header fields. Those works are directed towards finding efficient algorithms and implementation architectures for high speed routing, Quality of Ser...
Plants commonly respond to stressors by modulating the expression of a large family of calcium binding proteins including isoforms of the ubiquitous signaling protein calmodulin (CaM). The various plant CaM isoforms are thought to differentially regulate the activity of specific target proteins to modulate cellular stress responses. The mechanism(s) behind differential target activation by the ...
Collagen deposition is a hallmark of atherosclerosis. Although compromised collagen I degradation has been implied in the pathogenesis of atherosclerosis, the molecular mechanisms are still unclear. Thus, we determined the role of CD38, an enzyme involved in cellular calcium modulation and autophagic flux, in the regulation of collagen I degradation in coronary arterial myocytes (CAMs).In prima...
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