Vitamin D insufficiency is prevalent in chronic kidney disease (CKD) and associated with secondary hyperparathyroidism (SHPT) and increased risk of bone and vascular disease. Unfortunately, supplementation of stage 3 or 4 CKD patients with currently recommended vitamin D2 or D3 regimens does not reliably restore serum total 25-hydroxyvitamin D to adequacy (≥30ng/mL) or effectively control SHPT....

The role of calcifediol in the perception of chronic pain is a widely discussed subject. Low serum levels of calcifediol are especially common in patients with severe pain and fibromyalgia syndrome (FMS). We lack evidence of the role of vitamin D supplementation in these patients. To our knowledge, no randomized controlled trial has been published on the subject. Thirty women with FMS according...

Background. Previous research on the combined association of 25-hydroxyvitamin D [25(OH)D] and exocrine pancreas insufficiency may have been limited by restricted age variability and a lack of representation of both body weight and body mass index. There are still too few conclusive reports about conspicuous vitamin D metabolism according to pancreatic fecal elastase 1 (FE1) in obese patients. ...

Vitamin D deficiency following malabsorptive bariatric surgery can lead to osteomalacia. We report a patient with severe vitamin D deficiency following malabsorptive bariatric surgery successfully treated with calcifediol but not cholecalciferol. A 40-year-old woman, submitted to biliopancreatic diversion 20 years before and chronically treated with 50,000 IU cholecalciferol weekly, was admitte...

METAS: Avaliar as concentrações séricas de 25-hidroxivitamina D, 25 (OH) em pacientes osteoporóticos tratados por um ano com calcifediol.
 MÉTODOS: Foram estudados 156 osteoporose (23 homens e 133 mulheres) idade 71,9 ± 9,6 anos que haviam recebido tratamento calcifediol pelo menos ano. Noventa dois deles receberam 0,266 mg a cada 15 dias os 64 restantes mesma dose uma vez mês. Os níveis s...

Dear Preprints with the Lancet Readers, We removed this preprint due to concerns about description of research in paper. This led us initiate an investigation into study. Following conclusion study by National Centre Biomedical Research on Frailty and Healthy Aging (CIBERFES), Spain, report concluded that: 1) In elaboration manuscript correspondence authors Journal, there was a series mis...

1. The term vitamin D is used for a range of closely related steroid compounds which possess the property of preventing or curing vitamin D deficiency. These include alfacalcidol (1α-hydroxyvitamin D3), calcifediol (25-hydroxyvitamin D3), calcitriol (1α,25 dihydroxy-vitamin D3), cholecalciferol (vitamin D3), dihydrotachysterol and ergocalciferol (vitamin D2 or calciferol). In veterinary medicin...

Vitamin D1 Compound of ergocalciferol with lumisterol (stereoisomer of ergosterol) 1:1 ratio Vitamin D2 Ergocalciferol (made from ergosterol) Vitamin D3 Cholecalciferol (made from 7dehydrocholesterol in the skin) Vitamin D4 22-dihydroergocalciferol Vitamin D5 Sitocalciferol (made from 7-dehydrositosterol) Vitamin D6 Calciferol 25-(OH) Vitamin D Calcidiol or calcifediol; indicates no distinction...

BACKGROUND Patients with inflammatory bowel diseases (IBD) have an increased risk of clostridium difficile infection (CDI). Cathelicidins are anti-microbial peptides that attenuate colitis and inhibit the effect of clostridial toxins. Plasma calcifediol [25(OH)D] stimulates production of cathelicidins. AIM To examine the association between plasma 25(OH)D and CDI in patients with IBD. METHO...