Background: The lengths of CAG repeats in two spinocerebellar ataxia genes, SCA1 and SCA3, were analyzed to determine whether such repeats exist in higher numbers in infertile males. Materials and Methods: Blood samples were collected from healthy controls, oligozoospermia patients, and azoospermia patients. DNA fragments containing target CAG repeats were amplified by PCR with template DNA pur...

background despite the similar rate of hp infection, the rate of gastric cancer (gc) differs in different regions of the country. there are conflicting reports for using a panel of serologic tests such as pepsinogens i, ii (pg i and pg ii), and gastrin for population screening. we designed this study to assess healthy appearing adults in shiraz, southern iran in order to evaluate the correlatio...

A high prevalence of antibody to cag A has been observed in H. pylori seropositive patients (HP+) living in developed countries. This is felt to be correlated with the development of serious sequelae of this infection.  We examined the sero-prevalence of antibody to cag A and other specific H. pylori antigens in symptomatic and asymptomatic individuals living in Kashan.Sera from 37 patients who...

background: infectious agents have been suspected as a triggering factor for development of autoimmune thyroid disease (atd). some reports from western countries have suggested association between helicobacter pylori (hp) infection and atd. objective: to investigate the association of atd with cag a seropositivity in a population with high rate and early age of onset of hp infection. methods: i...

Background: Infectious agents have been suspected as a triggering factor for development of autoimmune thyroid disease (ATD). Some reports from Western countries have suggested association between Helicobacter pylori (HP) infection and ATD. Objective: To investigate the association of ATD with Cag A seropositivity in a population with high rate and early age of onset of HP infection. Methods: I...

huntington’s disease (hd) is an inherited neurodegenerative disorder characterized by chorea and progressive dementia. the mutation causing the disease has been identified as an unstable expansion of a tri-nucleotide (cag) n at the 5 end of the it 15 gene on chromosome 4. we analyzed the distribution of cag repeats in 66 iranian patients belonging to 66 unrelated families. we found one expanded...

a high prevalence of antibody to cag a has been observed in h. pylori seropositive patients (hp + ) living in developed countries. this is felt to be correlated with the development of serious sequelae of this infection.  we examined the sero-prevalence of antibody to cag a and other specific h. pylori antigens in symptomatic and asymptomatic individuals living in kashan. sera from 37 patients ...

Background: Anatomically myocardial bridging (MB) consists of either superficial myocardial fibers that traverse over the LAD or deep fibers that encircle the coronary artery. In this study, we present a patient with myocardial bridging, who was primarily diagnosed with coronary artery disease which did not properly respond to full-dose medical treatment but benefited from coronary artery bypas...