background & aim: spirulina (spirulina plantesis) and tea (camellia sinensis) has a long history of use in folk medicine. recently, they have been widely studied for their potential antioxidant properties. the present study investigated neuroprotective effect of spirulina and green tea extract against cadmium [cd]-induced brain lesions and to compare these effects with neuroprotective effec...

the aim of this study was to investigate the effects of administering antioxidants, including vitamin c and chitosan on oxidative stress markers in muscle as edible tissues of cyprinus carpio exposed to cadmium chloride. in this experiment, by exposing to 0.2 mg/l cadmium chloride for 21 days, fish were fed a normal diet, diet containing chitosan (1000 mg/kg diet), vitamin c (1000 mg/kg diet) o...

Background: Cadmium is a potential pollutant of the environment. It manifests cyto-toxic effects in different organs in animals. In the testis, changes due to disruption of the blood-testis barrier and oxidative stress have been noted. Therefore, the present study was carried out to investigate the potential protective effects of vitamin E and green tea extract in combination against cadmium (C...

The effect of cadmium chloride on green gram (Vigna radiata Linn.) was studied using the parameters like carbohydrates, protein, chlorophyll and oxidative enzymes like superoxide dismutase, catalase and peroxidase of leaves inorder to know the possible involvement of cadmium metal in the generation of oxidative stress. Results obtained in this work showed that the application of cadmium decreas...

background: cadmium (cd) intoxication can cause oxidative stress and involve the antioxi-dant defense system in hepatocytes. administration of vitamin c, chitosan, or a combination of both may prevent cd-induced oxidative damage. methods:cyprinus carpio were distributed into six groups. the control group received normal feed (group i). group ii was exposed to 0.2 mg.l-1 cadmium chloride. group ...

this investigation aimed to examine the protective function of vitamin e on rat bone marrow mesenchymal stem cells (mscs) treated with cadmium chloride. rat bone marrow mscs were extracted using flashing-out and cultured in dmem containing 10% fbs and 100 u/ml pen/strep. at the end of the third passage, cells were divided into 4 groups including control, cadmium chloride, cadmium chloride + vit...

Background: Cadmium (Cd) intoxication can cause oxidative stress and involve the antioxi-dant defense system in hepatocytes. Administration of vitamin C, chitosan, or a combination of both may prevent Cd-induced oxidative damage. Methods:Cyprinus carpio were distributed into six groups. The control group received normal feed (Group I). Group II was exposed to 0.2 mg.L-1 cadmium chloride. Gr...

This investigation aimed to examine the protective function of vitamin E on rat bone marrow mesenchymal stem cells (MSCs) treated with cadmium chloride. Rat bone marrow MSCs were extracted using flashing-out and cultured in DMEM containing 10% FBS and 100 U/ml Pen/Strep. At the end of the third passage, cells were divided into 4 groups including control, cadmium chloride, cadmium chloride + vit...

Cadmium is a most toxic heavy metal and an environmental pollutant. The present study was conducted to evaluate the antioxidant role of vitamin E in cadmium chloride (Cdcl2) induced testicular toxicity in rats. .Male wistar albino rats (n=6/group) were divided into control group (saline injected), untreated experimental groups (Single dose of 1mg and 2mg/kg BW, intraperitonially), and pretreate...

Salts of divalent cadmium are well-known human mutagens and carcinogens. In the present work, the ability of vitamin C to modulate genotoxic effects of cadmium chloride on human lymphocytes was assessed using single cell gel electrophoresis (comet assay). Vitamin C at 20 and 100 micromol/l and cadmium at 5, 30 and 150 micromol/l significantly increased the tail moment of lymphocytes. Vitamin C ...